Results 171 to 180 of about 45,955 (291)

Pharmacogenetic hSLCO1B1*14‐Guided Dosing of Methotrexate in Transgenic Arthritic Mice Normalizes Exposure and Response

open access: yesClinical and Translational Science, Volume 19, Issue 1, January 2026.
Summary of SLCO1B1 impact on methotrexate treatment of juvenile idiopathic arthritis, and the promise of SLCO1B1‐guided dosing. Polymorphisms to the SLCO1B1 gene influence MTX PK and JIA treatment outcomes. Preclinical studies demonstrate reduced MTX exposure and treatment efficacy with the SLCO1B1*14 allele linked to increased hepatic OATP1B1 ...
Felicia Gooden   +10 more
wiley   +1 more source

Artificial intelligence in genitourinary pathology

open access: yesHistopathology, Volume 88, Issue 1, Page 353-373, January 2026.
Artificial intelligence (AI) is now practical in genitourinary pathology. We synthesize evidence and economics into a two‐part playbook: VALIDATED (governance) and ORCHESTRATE (operations), to safely deploy AI tools across prostate, bladder, kidney and testis.
Ankush U Patel   +2 more
wiley   +1 more source

Seed‐Borne Spirosoma pollinicola in Commercial Hazelnuts: A Global Survey of Microbial Presence and Allergen Diversity

open access: yesPlant, Cell &Environment, Volume 49, Issue 1, Page 398-409, January 2026.
ABSTRACT Serious allergic reactions are increasing globally. Within this context, fatal anaphylaxis from hazelnut allergies is a critical public health concern. Hazelnuts, which are a common ingredient of many foods, contain many proteins that cause severe allergic reactions.
Barbara Karpinska   +4 more
wiley   +1 more source

Integrative Multiscale Analysis Reveals EFNA1‐Driven Immune Remodeling Promotes Colorectal Cancer Lymph Node Metastasis

open access: yesHuman Mutation, Volume 2026, Issue 1, 2026.
Background Nodal involvement constitutes a pivotal prognostic indicator in colorectal carcinoma, yet the transcriptional machinery governing lymphatic dissemination and tumor‐microenvironment crosstalk remains poorly elucidated. Conventional bulk sequencing methodologies lack sufficient resolution to deconvolve functionally distinct malignant subclones
Wu Ning   +6 more
wiley   +1 more source

Commodity risk assessment of oak and walnut logs from the US

open access: yesEFSA Journal, Volume 24, Issue 1, January 2026.
Abstract The European Commission submitted to the EFSA Panel on Plant Health a Dossier from the United States proposing the use of a vacuum–steam–heat treatment as a stand‐alone phytosanitary measure to mitigate the risk of entry of Bretziella fagacearum, Geosmithia morbida and its vector Pityophthorus juglandis (thousand cankers disease complex) into ...
EFSA Panel on Plant Health (PLH)   +30 more
wiley   +1 more source

Commodity risk assessment of Petunia spp. and Calibrachoa spp. unrooted cuttings from Uganda

open access: yesEFSA Journal, Volume 24, Issue 1, January 2026.
Abstract The European Commission requested the EFSA Panel on Plant Health to evaluate the likelihood of pest freedom at entry in the EU, including both regulated and non‐regulated pests, potentially associated with unrooted cuttings of the genera Petunia and Calibrachoa produced under physical isolation in Uganda.
EFSA Panel on Plant Health (PLH)   +34 more
wiley   +1 more source

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