Results 51 to 60 of about 255,613 (281)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Forearm Compartment Syndrome Caused by Reperfusion Injury

Case Reports in Vascular Medicine, 2014
Compartment syndrome is commonly seen following lower extremity ischemia. However, upper extremities’ compartment syndrome, especially after any vascular surgical procedures, is infrequent. Herein we report a case of an acute forearm compartment syndrome
Ufuk Sayar, Tanıl Özer, İlker Mataracı   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Modeling of breath methane concentration profiles during exercise on an ergometer [PDF]

, 2016
We develop a simple three compartment model based on mass balance equations which quantitatively describes the dynamics of breath methane concentration profiles during exercise on an ergometer.
Jandacka, Martin, King, Julian, Mochalski, Pawel, Mohacsi, Arpad, Ruzsanyi, Vera, Szabo, Anna, Szabo, Gabor, Teschl, Gerald, Teschl, Susanne, Unterkofler, Karl   +9 more
core   +2 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Utility of laboratory markers in evaluating for acute compartment syndrome in the emergency department

Journal of the American College of Emergency Physicians Open, 2021
Background Acute compartment syndrome is diagnosed by clinical examination with the aid of direct compartmental measurement. Previous work suggested using several laboratory markers that may suggest ongoing acute compartment syndrome in hospitalized ...
Gregory S. Weingart, Phillip Jordan, Kei‐Lwun Yee, Lauren Green   +3 more
doaj   +1 more source

Acute Isolated Thenar Compartment Syndrome in a Patient with Evans Syndrome: A Case Report

Clinical Practice and Cases in Emergency Medicine, 2022
Introduction: Acute compartment syndrome of the hand is a rare medical emergency, most often associated with trauma or fracture. Case Report: Here, we describe a rare case of isolated thenar compartment syndrome of the hand in the absence of major trauma
Elisabeth Jiang, Kevin H. Kim, Alan Babigian   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Abdominal Compartment Syndrome

Acta Chirurgica Belgica, 2001
Abdominal compartment syndrome may be defined as the deleterious pathophysiologic consequences of a significant increase in intra-abdominal pressure. These alterations can affect respiratory mechanics, cardiovascular system, regional blood flow, renal function, urine output, and intracranial pressure.
Loi, Patrizia, De Backer, Daniel, Vincent, Jean Louis   +2 more
openaire   +5 more sources

Abdominal Compartment Syndrome in Surgical Patients

The Annals of African Surgery, 2017
Background: The deleterious effects of intra-abdominal hypertension and abdominal compartment syndrome, affect almost every system. Patients at risk are critically ill, in whom it leads to altered organ perfusion and end-organ dysfunction/failure.
Alex Muturi, Daniel Ojuka, Andrew Kibet
doaj