ABSTRACT The present study aimed to evaluate the developmental morphometry of the paranasal sinuses using computed tomography (CT) in subjects aged 1–25 years and to characterize age‐related changes in sinus dimensions, volume, and surface area throughout childhood, adolescence, and young adulthood.
Ceyda Şevval Çetin +4 more
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Beyond the Catalogue: Design and Biological Enrichment as the Next Priorities in Higher-Risk MDS Drug Development. [PDF]
Zeidan AM, Bono P, Williamson J.
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The ToC image shows a porous B, N‐doped carbon nanotube decorated with B‐doped Cu nanoparticles for nitrate‐to‐ammonia conversion. The unique structure enhances charge transport, promotes the adsorption and activation of key intermediates, alters the rate‐determining step, suppresses hydrogen evolution, and improves NH3 yield and Faradaic efficiency ...
Xiangding Li +7 more
wiley +1 more source
Regional oximetry for diagnosing compartment syndrome: a scoping review. [PDF]
Tang LY +5 more
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From Caffeine to Aspirin: Everyday Molecules as Triggers for Genetically Encoded Proximity Systems
This Perspective article highlights how familiar dietary ingredients and over‐the‐counter (OTC) drugs (such as caffeine and its metabolites, SA, and aspirin) can be repurposed as clinically translatable chemical triggers for genetically encoded proximity systems.
Mingguang Cui +5 more
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Intra-Abdominal Compartment Syndrome Secondary to Massive Pelvic Müllerian Tumor. [PDF]
Shah S, Kalra TS, Atif D, Niazi U.
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Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor +12 more
wiley +1 more source
Association Between Number of Positive Pedowitz Criteria and Outcome After a Fasciotomy for Lower Leg Chronic Exertional Compartment Syndrome. [PDF]
van Heeswijk K +4 more
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From Prediction to Decision Making: PBPK and QSP as Regulatory‐Grade NAMs
New approach methodologies (NAMs) encompass a diverse and rapidly evolving set of experimental and computational tools designed to generate human‐relevant mechanistic data for use in drug development and regulatory decision making. Experimental NAMs provide insights into drug disposition, pharmacological activity, and disease biology that are difficult
Karen Rowland Yeo, Piet H. van der Graaf
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Renal Amyloidosis in Pediatric Autoinflammatory Syndromes: Subclinical Onset, Early Biomarkers, and Clues for Timely Characterization and Interventions. [PDF]
Arsiwala N, Rigante D.
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