Results 81 to 90 of about 36,015 (294)

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Acute compartment syndrome: Reducing the risk

, 2008
Acute limb compartment syndrome is a surgical emergency characterized by raised pressure within an unyielding tissue compartment. Although there is commonly a history of trauma there are a number of causes of compartment syndrome, which includes ...
Nanchahal, J, Pearse, MF
core   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

FACE2 GENE - New opportunity for early and timely diagnosis of Eye Dysmorphic Syndromes

, 2017
Въведение: Ранната и своевременна диагностика на дисморфичните синдроми продължава да е истинско изпитание и предизвикателство за педиатри, офталмолози, клинични генетици, дисморфолози. Над 80 % от дисморфичните синдроми имат различни очни прояви.
Popova, A.; Children`s eye compartment, Multispecialty University Hospital `Alexandrovska`, Medical University - Sofia
core   +1 more source

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

Advanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin, Xinran Deng, Haonan Wang, Yamei Jiang, Jian Sun, Hailin Ding, Ming Ye, Xiaoting Wang, Yu Wang, Li Yuan, Zhenju Song, Xinhua Lin, Shenfei Sun, Ning Jiang   +13 more
wiley   +1 more source

Fasciotomía profiláctica y síndrome "compartimental" de las extremidades: ¿existen indicaciones justificables? Prophylactic fasciotomy and compartment syndrome of the extremities: are there justifiable indications?

Revista Colombiana de Cirugía, 2011
Introducción. La fasciotomía es la principal intervención para tratar el síndrome "compartimental"; no obstante, sería ideal prevenir su aparición. El mismo procedimiento quirúrgico, pero profiláctico, se plantea como la mejor opción, aunque para algunos
Juan Carlos Gómez-Hoyos, Carlos Hernando Morales   +1 more
doaj  

Exercise-Induced Paraspinal Muscle Rhabdomyolysis with Seconary Compartment Syndrome: A Case Report

대한영상의학회지, 2019
Lumbar paraspinal compartment syndrome is an uncommon cause of acute lower back pain. It can result from intense physical activity or as a complication of surgery or medication.
Soong Moon Cho, Ghi Jai Lee, Yong Jun Jin, Ki Hwan Kim, Kyoung Eun Lee, Jae-Chan Shim, Dae Hyun Hwang, Ho Kyun Kim   +7 more
doaj   +1 more source

Abdominal compartment syndrome [PDF]

F1000 Medicine Reports, 2009
The abdominal compartment syndrome (ACS) was first described in surgical patients with abdominal aortic aneurysm repair, trauma, bleeding, or infection, but in recent years it has also been described in patients with other pathologies such as burn injury and sepsis and in medical patients. This F1000 Medicine Report is intended to provide critical care
openaire   +3 more sources

MDS Stem Cell Biology

, 2013
The clinical heterogeneity of patients with myelodysplastic syndromes suggests that there must also be a broad range of pathogenetic abnormalities that underlie this disorder.
Nimer, Stephen D, H. Joachim Deeg, Greenblatt, Sarah M, Deeg, H. Joachim, Stephen D. Nimer, Sarah M. Greenblatt   +5 more
core   +1 more source

PRC2.1 Coordinates Peri‐Nucleolar H3K27me3‐Enriched Heterochromatin Organization and NPM1 Pentamerization to Maintain Nucleolar Integrity

Advanced Science, EarlyView.
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu, Wenqin Wang, Shuyun Chen, Gangyi Zhu, Zhen Wu, Yue Gu, Jingwen Xiong, Xu Zhang, Heng Liu, Kyoichi Isono, Youming Zhang, Jingjing Cao, Xiangzhi Li   +12 more
wiley   +1 more source