Tracheal Replacement Therapy with a Stem Cell-Seeded Graft: Lessons from Compassionate Use Application of a GMP-Compliant Tissue-Engineered Medicine [PDF]
, 2017 Tracheal replacement for the treatment of end-stage airway disease remains an elusive goal. The use of tissue-engineered tracheae in compassionate use cases suggests that such an approach is a viable option.
Ansari, T +22 more
core +1 more source
Cabazitaxel in the treatment of metastatic castration-resistant prostate cancer: patient selection and special considerations. [PDF]
, 2017 Cabazitaxel is an effective chemotherapeutic agent used in the treatment of metastatic castration-resistant prostate cancer (mCRPC) refractory to docetaxel.
Hoffman-Censits, Jean, Patel, Sheel
core +3 more sources
One Health, 2020 Recent international epidemics of coronavirus-associated illnesses underscore the urgent medical and public health need for vaccine development and regulatory body approved therapies.
E. Susan Amirian, Julie K. Levy
doaj +1 more source
Remdesivir use in the coronavirus disease 2019 pandemic: A mini-review
Journal of Microbiology, Immunology and Infection, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative viral pathogen of coronavirus disease 2019 (COVID-19), appears to have various clinical presentations and may result in severe respiratory failure.
Chih-Jen Yang +6 more
doaj +1 more source
Liver transplantation for viral hepatitis in 2015 [PDF]
, 2016 Liver transplantation (LT) is a life-saving treatment for patients with end-stage liver disease and for patients with liver cell cancer related to liver disease.
Bortoluzzi, Ilaria +8 more
core +1 more source
Current regulatory approaches for accessing potential COVID-19 therapies
Journal of Pharmaceutical Policy and Practice, 2020 This commentary aims to elaborate challenges in the regulatory approaches for accessing and investigating COVID-19 potential therapies either with off-label use, compassionate use, emergency use or for clinical trials.
Vesa Halimi +6 more
doaj +1 more source
Interventions for adjustment, impaired self-awareness and empathy [PDF]
, 2017 No abstract ...
Ashworth, Fiona +2 more
core +1 more source
Post-trial access to treatment for patients participating in clinical trials
Perspectives in Clinical Research, 2015 Clinical trials are the mainstay for bringing out newer and better drugs to serve the mankind. By virtue of participating in a clinical trial, a patient receives access to the newer drugs/therapies, but nothing is generally being offered to them once ...
Dinesh Chandra Doval +2 more
doaj +1 more source
Improving empathy of physicians through guided reflective writing [PDF]
, 2012 Objectives: This study was designed to explore how guided reflective writing could evoke empathy and reflection in a group of practicing physicians. Methods: Total participants recruited included 40 staff physicians at Cleveland Clinic, a tertiary care ...
Calabrese, Leonard +6 more
core +2 more sources
Off-label antineoplastic drugs. An effectiveness and safety study [PDF]
Farmacia Hospitalaria, 2017 Objective: The use of antineoplastic medicines in special situations is common in clinical practice; it is strongly regulated and there is little information on its outcomes.
Cristina Arroyo Álvarez +5 more
doaj +1 more source