Results 41 to 50 of about 243,560 (261)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Measurement Uncertainty of Radiated Electromagnetic Emissions in In Situ Tests of Wind Energy Conversion Systems [PDF]
Advances in Radio Science, 2018 The electromagnetic (EM) emissions of wind energy conversion systems (WECS) are evaluated in situ. Results of in situ tests, however, are only valid for the examined equipment under test (EUT) and cannot be applied to series production as samples, as ...
S. Koj, A. Hoffmann, H. Garbe
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Spherical Equivalent Dipole Array Theory and Its Applications to Complex Electromagnetic System
IEEE Access, 2019 The equivalent dipole array is an effective method for emission source modeling to solve practical electromagnetic engineering problems. In this paper, a spherical equivalent dipole array method (SEDAM) is proposed to model practical and complex ...
Jing Nie, Shunchuan Yang, Donglin Su
doaj +1 more source
Applied Sciences, 2023 The construction of multilayer rail transit systems is a necessary way to realize “modern metropolitan areas on rail”, improve resource sharing, and increase travel services, where data integration is of utmost importance. To break data silos and realize
Xin Geng +3 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
A Novel Beam Steerable Antenna Employing Tunable High Impedance Surface With Liquid Crystal
IEEE Access, 2020 A novel beam steerable antenna employing tunable high impedance surface with liquid crystal is proposed. This antenna utilizes three microstrip patches as the radiators and a tunable high impedance surface based on liquid crystal as the ground plane.
Jun Shu, Yueping Zhang, Ziyang Zheng
doaj +1 more source
Lightning Nowcasting Using Solely Lightning Data
Atmosphere, 2023 Lightning is directly or indirectly responsible for significant human casualties and property damage worldwide. A timely prediction of its occurrence can enable authorities and the public to take necessary precautionary actions resulting in diminishing ...
Ehsan Mansouri +4 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source