Results 31 to 40 of about 180,480 (256)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
OENO One, 1996 Defoliation and decapitation experiments showed that the growth of a grapevine leaf was inhibited by both the terminal bud and the younger higher leaves. There is a phenomenon of synergy between these two influences.
Jean-Claude Fournioux
doaj +1 more source
Differential vascular growth in postpneumonectomy compensatory lung growth [PDF]
The Journal of Thoracic and Cardiovascular Surgery, 2007 After pneumonectomy, compensatory growth occurs in the remaining lung. The vascular response during this growth and how individual lobes of the lung respond are not well understood. The aim of our study was to characterize vascular growth among individual lobes of the lung after pneumonectomy and determine whether changes in relative blood flow ...
Fernandez, Lucas G. +5 more
openaire +2 more sources
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Effect or ractopamine on growth and body composition of pigs during compensatory growth*
Animal, 2009 The purpose of this study was to measure the growth and body composition of pigs during normal or compensatory growth from 60 to 100 kg, without (cont) or with ractopamine (rac) supplementation (20 mg/kg of diet).
A.D. Mitchell
doaj +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Diet Dilution and Compensatory Growth in Broilers
Poultry Science, 1991 Two experiments were conducted to note the response of broiler chickens to degrees of diet dilution from 4 to 11 days of age. In Experiment 1, broilers were fed conventional broiler diets from 0 to 4 and 11 to 56 days of age. From 4 to 11 days, birds were fed a conventional corn and soybean meal broiler starter, or the same diet in which major ...
A, Leeson, J D, Summers, L J, Caston
openaire +2 more sources
GROWTH OF AMUR FLATHEAD ASP PSEUDASPIUS LEPTOCEPHALUS (PALLAS, 1776)
Известия ТИНРО, 2020 Linear and weight growth of amur flathead asp Pseudaspius leptocephalus is described on the base of the measurements data collected on the lower Amur (from Nizhneleninskoe village to the mouth) in 2004–2018, using von Bertalanffy growth equation. Age was
N. N. Semenchenko
doaj +1 more source