Results 131 to 140 of about 132,789 (268)

Defining Global Health Diplomacy: Assessing United States Global Health Diplomacy actors' knowledge, skills, and competencies. [PDF]

PLOS Glob Public Health
Esapebong-Ray F, McDonnell K, Katz R.
europepmc   +1 more source

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

Advanced Science, EarlyView.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Developing a national competency framework for pediatric hospital medicine in Canada using the Delphi method. [PDF]

Can Med Educ J
Vetere P, Walsh CM, Al Maawali A, Puran A, Beran TN, Bismilla Z, Cooke S.   +6 more
europepmc   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source

Formalizing digital health competencies for the health workforce in Ukraine. [PDF]

Front Public Health
Zvinchuk O, Sergeeva L, Nanaieva T, Terentyuk V, Aleksandrenko H.   +4 more
europepmc   +1 more source

Is the Theory of Competences Competent?

Управленческое консультирование, 2018
Today the theory of competences is extensively introduced into the practice of teaching, training and certification of qualified personnel . Many issues are published nowadays to provide well-grounded reasons of the validity and effectiveness of this theory application.
openaire   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

The International Sports Physiotherapy Competencies and Standards 2025: The SportsComp Project on Higher Education to Improve Competency in Sports Physiotherapy. [PDF]

Int J Sports Phys Ther
Constantinou M, Ramponi C, Tassignon B, Dick E, Lathouwers E, Arend M, Lepasalu L, Hirvonen A, Sihvonen S, Paasu-Hynynen S, Kapreli E, Tsokani A, Strimpakos N, De Michelis Mendonça L, Verschueren J.   +14 more
europepmc   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

Advanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou, Yongfeng Chen, Longyou Xiao, Wei Qi, Tianshu Du, Qiang Sun, Borui Xue, Qinghe Zhao, Pengfei Xie, Zi Ye, Fei Han, Lingli Guo, Yang Jiao, Ranran Zhang, Hong Jia, Xiao Huang, Jianwei Guo, Peng Wang, Huayi Wang, Yuanrui Wang, Wenjing Chen, Haining Wu, Liumin He, Dawei Zhang   +23 more
wiley   +1 more source

The Differences in Necessary Competencies, Skills, and Performance Abilities Among Thai Board-Certified Occupational Medicine Physicians and Basic Occupational Medicine Certified Physicians

Journal of Multidisciplinary Healthcare
Pachara Sasanawin,1 Vithawat Surawattanasakul,2,3 Shewarat Prasan,1 Kitipong Banomyong1 1Occupational and Environmental Medicine Excellent Center, Nopparat Rajathanee Hospital, Bangkok, Thailand; 2Department of Community Medicine, Faculty of Medicine ...
Sasanawin P, Surawattanasakul V, Prasan S, Banomyong K   +3 more
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