Results 91 to 100 of about 1,425,115 (408)

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Trust-based Modelling of Multi-criteria Crowdsourced Data

open access: yesData Science and Engineering, 2017
As a recommendation technique based on historical user information, collaborative filtering typically predicts the classification of items using a single criterion for a given user.
Fátima Leal   +3 more
doaj   +1 more source

Maximizing Competency Education and Blended Learning: Insights from Experts [PDF]

open access: yes, 2015
In May 2014, CompetencyWorks brought together twenty-three technical assistance providers to examine their catalytic role in implementing next generation learning models, share each other's knowledge and expertise about blended learning and competency ...
Chris Sturgis, Susan Patrick
core  

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Competence and competence development [PDF]

open access: yes, 2012
What are today's main concepts and theories - and the main stakes - associated with the issue of competences in organizations? Several topics are discussed, including competence issues regarding the evolution of work, professionalization, competence evaluation, competence management, and the competences of adult educators and trainers, as well as ...
openaire   +2 more sources

Predictive capability of foundational concepts tests for problem-solving using machine learning concepts: Evaluating project-based learning courses in artificial intelligence literacy education

open access: yesComputers and Education: Artificial Intelligence
In the artificial intelligence (AI) era, secondary and university students should be able to apply AI for problem-solving. This study designed and evaluated an AI literacy programme to enhance understanding of machine learning concepts.
Siu Cheung Kong, Chunyu Hou
doaj   +1 more source

Automatic validation of learning object compositions [PDF]

open access: yes, 2006
Course construction using reusable learning objects is becoming ever more popular due to its’ efficiency. The course creator who uses this methodology may face problems due to the fact that he or she is not as intimately involved in the creation of every
Melia, Mark, Pahl, Claus
core  

An information technology competency model and curriculum [PDF]

open access: yes, 2016
This paper addresses the progress made by the Association for Computing Machinery (ACM) and the IEEE Computer Society (IEEE-CS) in developing a competency model and curricular guidelines for four-year degree programs in information technology.
Alrumaih, Hala   +2 more
core   +2 more sources

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Marine Risers for Deepwater Oil and Gas Exploitation: Research Progress and Prospect [PDF]

open access: yes中国工程科学
As key equipment connecting offshore platforms to subsea pipelines, marine risers are a critical component of the overall system for deepwater oil and gas exploitation and are crucial for the high-quality development of the marine oil industry.
Xiao Wang   +8 more
doaj   +1 more source

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