Results 71 to 80 of about 10,533,556 (401)
Risks, risk assessment and risk competence in toxicology
German medical science : GMS e-journal, 2015 Das Verständnis der toxischen Wirkungen von Stoffen setzt ein gutes Verständnis der Physiologie bzw. Biochemie voraus. Das häufig beschriebene mangelnde Verständnis in der Bevölkerung für die Pharmakologie und Toxikologie beruht deshalb zu einem großen Teil auf den mangelnden Kenntnissen der erforderlichen Grundlagen.
Stahlmann, R, Horvath, A
openaire +4 more sources
Authorial Voice, Implied Audiences and the Drafting of the 1988 AIDS National Mailing [PDF]
, 1993 Dr. Veeder analyzes changes throughout many drafts of the 1988 ANM and finds that the process of negotiated drafting contributed to its success. She also concludes that risk communicators should focus attention on audience needs rather than competing ...
Veeder, Mary Harris
core +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Frontiers in OncologyObjectiveThe study aimed to build and validate a competitive risk nomogram to predict the cumulative incidence of hepatocellular carcinoma (HCC) for patients with hepatitis B virus (HBV)-related cirrhosis.MethodsA total of 1401 HBV-related cirrhosis ...
Dandan Guo +7 more
doaj +1 more source
Frontiers in Oncology, 2021 ObjectivesHerein, we purposed to establish and verify a competing risk nomogram for estimating the risk of cancer-specific death (CSD) in Maxillary Sinus Carcinoma (MSC) patients.MethodsThe data of individuals with MSC used in this study was abstracted ...
Mingbin Hu +5 more
doaj +1 more source
The Competing Risk of Death in Longitudinal Geriatric Outcomes
Journal of The American Geriatrics Society, 2018 To address the competing risk of death in longitudinal studies of older persons, we demonstrate sensitivity analyses that evaluate robustness of associations between exposures and three outcome types: dichotomous, count, and time to event.
T. Murphy +5 more
semanticscholar +1 more source
Modelling competing risks in nephrology research: an example in peritoneal dialysis [PDF]
, 2013 BACKGROUND: Modelling competing risks is an essential issue in Nephrology Research. In peritoneal dialysis studies, sometimes inappropriate methods (i.e.
Cabrita, A. +4 more
core +2 more sources
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Frontiers in Public Health, 2022 ObjectivesDrug-resistant tuberculosis remains a serious public health problem worldwide, particularly in developing countries, including China. This study determined treatment outcomes among a cohort in Guangzhou, China, and identified factors associated
Zhiwei Li +6 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source