Results 71 to 80 of about 1,167,728 (343)
How to Bootstrap Aalen-Johansen Processes for Competing Risks? Handicaps, Solutions and Limitations
, 2014 Statistical inference in competing risks models is often based on the famous Aalen-Johansen estimator. Since the corresponding limit process lacks independent increments, it is typically applied together with Lin's (1997) resampling technique involving ...
Dobler, Dennis, Pauly, Markus
core +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
International Journal of Radiation Oncology*Biology*Physics, 2021 Basak, Ramsankar +2 more
openaire +2 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
American Heart Journal PlusStudy Objective: Despite advances, myocardial infarction remains a significant public health concern, with survival being a crucial outcome measure. While all-cause mortality is well-studied, less is known about causes of death following an infarction ...
Tamás Ferenci, András Jánosi
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Competing‐risks model for prediction of small‐for‐gestational‐age neonate from maternal characteristics, serum pregnancy‐associated plasma
, 2020 Ioannis Papastefanou +5 more
openalex +1 more source
COMPETING RISKS IN THE SUBURBANIZATION OF AGRICULTURAL LAND [PDF]
The rapid change in the character of land use in traditional agricultural regions of the Midwest has led to public concern in recent years. As a result, policy makers have attempted to forge novel ways to cope with problems associated with loss of ...
Hite, Diane +3 more
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Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
The Lancet Regional Health. AmericasSummary: Background: The incidence of infections from arthropod-borne viruses, including chikungunya and dengue, is increasing globally. We used nationwide data collected over a decade in Brazil to examine the factors associated with hospitalisation, in-
Thiago Cerqueira-Silva +9 more
doaj +1 more source