Results 71 to 80 of about 1,183,596 (299)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Comparison of all-cause and cause-specific mortality after myocardial infarction – a Hungarian registry study

American Heart Journal Plus
Study Objective: Despite advances, myocardial infarction remains a significant public health concern, with survival being a crucial outcome measure. While all-cause mortality is well-studied, less is known about causes of death following an infarction ...
Tamás Ferenci, András Jánosi
doaj   +1 more source

Unemployment Duration: Competing and Defective Risks [PDF]

This paper examines the determinants of unemployment duration in the framework of a competing risks model, where the destination states are employment and inactivity.
John T. Addison, Pedro Portugal
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Competing risks [PDF]

Lifetime Data Analysis, 2014
Jason, Fine, Bo Henry, Lindqvist
openaire   +2 more sources

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Competing risks: Competing questions [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2017
Jeevanantham, Rajeswaran, Eugene H, Blackstone   +1 more
openaire   +2 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Hospitalisation, mortality and years of life lost among chikungunya and dengue cases in Brazil: a nationwide cohort study, 2015–2024Research in context

The Lancet Regional Health. Americas
Summary: Background: The incidence of infections from arthropod-borne viruses, including chikungunya and dengue, is increasing globally. We used nationwide data collected over a decade in Brazil to examine the factors associated with hospitalisation, in-
Thiago Cerqueira-Silva, Luciana L. Cardim, Enny Paixão, Marta Rossi, Andreia Costa Santos, André Portela F de Souza, Gervasio Santos, Mauricio L. Barreto, Elizabeth B. Brickley, Julia M. Pescarini   +9 more
doaj   +1 more source

Features of survival analysis on patients on the «waiting list» for kidney transplantation

Бюллетень сибирской медицины, 2019
Survival analysis is one of the most common methods of statistical analysis in medicine. The statistical analysis of the transplantation (or death) probability dependent on the waiting time on the "waiting list" is a rare case when the survival analysis ...
A. B. Zulkarnaev
doaj   +1 more source