Results 51 to 60 of about 361,461 (265)

The Role of Psychological Qualities in the Process of the Formation of Sports Skill of Young Basketball Players

Фізичне виховання, спорт і культура здоров’я у сучасному суспільстві, 2018
Purpose: to determine the level of the development of indices of the influence of the important psychological qualities and the personality characteristics that defines the effectiveness of the competitive activity of young basketball players in the ...
Anatoly Rovniy, Vladlena Pasko
doaj   +5 more sources

ESTIMATION OF COMPETITIVE ACTIVITY IN SYNCHRONIZED SWIMMING

Physical Education of Students, 2013
Aim – is to develop the approach to technical complexity estimation of free routine composition in synchronized swimming. Were analyzed and considered free routine compositions of the strongest swimmers in European and World Championships during the ...
L.M. Shul'ga, T.I. Rudkovskaya
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Repeated Acceleration Activity in Competitive Youth Soccer

Central European Journal of Sport Sciences and Medicine, 2016
Soccer match-play is increasingly characterised by short, high-speed bursts reliant on the ability to accelerate. Performance is impaired after peak acceleration activity and during the second half and may compromise a player’s effectiveness.
Steve Atkins, David J. Barron, Chris Edmundson, Dave Fewtrell   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

TECHNICAL TRAINING OF WOMEN’S FOOTBALL PLAYERS

Вестник Кемеровского государственного университета, 2014
The paper focuses on technical training of women’s football players. The data of pedagogical observations over competitive activity during the official matches of the Russian championship among women’s teams are provided. The quantitative and qualitative
N. V. Trusova, L. N. Baraborkina, A. V. Sapego, E. V. Kozyreva   +3 more
doaj  

Modeling of competitive activity of skilled athletes specialized at 1500 m distance on short-track skating

Physical Education of Students, 2013
Background: Models of competitive activity at the 1500 m distance on short-track skating are developed on the basis of defining the relationship between sports results and major characteristics which describe speed of running at different parts of the ...
O.S. Kholodova
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Competitive Inhibition of Enzyme Activity by Urea

Journal of Biological Chemistry, 1961
SUMMARY Urea Inhibition of fifetallo-enzymes--From the data here presented, it appears that, in general, urea is relatively ineffective as an inhibitor of those metallo-enzymes whose metal component is involved in the formation of the enzyme-substrate complex.
K V, RAJAGOPALAN, I, FRIDOVICH, P, HANDLER   +2 more
openaire   +2 more sources