Results 31 to 40 of about 1,568,766 (320)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Modern Competitive Strategy Firm
The article deals with problems of an ever increasing number of cases of successful application of old combat strategies in business practice. Nevertheless, the author refuses the so called “direct conflict“ of firms, when it is really fought for victory
František Bartes
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
PERUMUSAN STRATEGI PERUSAHAAN BERDASARKAN COMPETITIVE ADVANTAGE
Perusahaan Tenun Ikat Lestari Indah adalah perusahaan pembuatan kain dengan alat tenun bukan mesin. Dalam menjalankan bisnisnya, perusahaan menghadapi berbagai kendala, diantaranya daya beli masyarakat menurun akibat situasi perekonomian yang tidak ...
Endah Utami, Ali Imron
doaj +3 more sources
Dinamika lingkungan bisnis saat ini telah menyulitkan perusahaan untuk memperoleh keunggulan yang berkelanjutan. Prilaku pesaing semakin sulit diprediksi sehingga strategi bersaing perusahaan sering kali tidak cukup kuat untuk mempertahankan daya ...
Yudi Pramudiana +2 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
BUSINESS COMPETITORS AND COMPETITIVE ADVANTAGE [PDF]
The paper presents the concept of competition, both from the perspective of the economic sector –where it is characteristic for pure monopole, oligopoly, monopole competition and pure competition, as well asfrom the market’s point of view – where it ...
SUCIU TITUS
doaj
Competitive Advantage Analysis in Pharmacy Companies
Article analyzes competitive advantage theoretical aspects and also competitive advantage in pharmacy sector in Lithuania. Competitive advantage is what all (competing) business strategies are directed to. Many factors can provide a competitive advantage;
Margarita Išoraitė
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
BUILDING COMPETITIVE ADVANTAGE THROUGH MARKETING, MANUFACTURING AND ENVIRONMENTAL MANAGEMENT STRATEGY: A CASE STUDY OF METAL PRODUCT SMEs IN TEGAL [PDF]
This research investigates how the marketing strategy, manufacturing strategy and environment management create SMEs competitive advantage that will improve SMEs business performance. It gives both theoretical and managerial implications about steps must
PERDHANA, Mirwan Surya +1 more
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