Results 61 to 70 of about 1,568,766 (320)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
A Importância da Visão Baseada em Recursos na Explicação da Vantagem Competitiva
Revista de Economia Mackenzie, 2006 The article reveals the theoretical implications of de Resource-Based View for understanding the firm competitive advantage. The dominant version to analysis of competitive advantage is represented by authors connected to Organizational Economics ...
Jucélio Kretzer +1 more
doaj
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Comparative Advantage, Competitive Advantage, and U.S. Agricultural Trade [PDF]
International Relations/Trade,
White, T. Kelley
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
, 2020 In theory, competitive advantage is “the delivering of superior value to customers and, in doing so, earning an above average return for the company and its stakeholders.” There is a discussion of the roots of advantage in firm‐specific imperfections and an elaboration of the major routes to achieving advantage.
McGee, John +2 more
openaire +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Japan's new competitive advantage: the arguments and proposals for structural reorientation [PDF]
, 2010 According to the AFP (Gazeta Wyborcza of 08 Dec. 2009), in the third quarter of 2009 the Japanese economy finally showed some signs of recovery and reached positive values; unemployment also dropped from 5.3% to 5.1% between September and October.
Młodawska, Jolanta
core +2 more sources
OBJECTIVES FOR A COMPETITIVE MARKET ADVANTAGE [PDF]
Business Excellence and Management, 2013 The paper analyses the present market that is a continual evolution and underlines the main objectives a company has to concentrate in order to obtain increasingly results.
Cătălin Cristian BABALÂC
doaj
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source