Results 41 to 50 of about 23,348,161 (293)
The preparation and study of anti-idiotypic (secondary) antibodies (Ab2) against monoclonal primary antibodies (Ab1) specific to biologically active molecules with a known structure is of great scientific and practical importance.
A. V. Trofimov +11 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Re-reengineering the dream: agility as competitive adaptability [PDF]
Organizational adaptation and transformative change management in technology-based organizations is explored in the context of collaborative alliances.
Allan F. McLay
core
The Importance of Competitive Analysis. Competitive Strategies
<p dir="ltr"><span>Competitive analysis is a fundamental aspect of strategic planning in the financial-banking sector. Understanding competitors, their objectives, strategies, strengths, and weaknesses enables financial institutions to position themselves effectively in the market.
openaire +1 more source
Introduction. The construction sector reacts to changes with a significant lag, slowing down longer than other industries during difficult periods and recovering longer after the crisis.
A. G. Chekalov, O. V. Berezhnaya
doaj +1 more source
The Mutual Benchmarking Method for Smes’ Competitive Strategy Development
Competitive advantage is a relative feature, evaluated in respect of other competing enterprises. The gaining of sustainable competitive advantage is conditioned by knowledge of own performance and the results of the competitive environment.
Rostek Katarzyna
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Improving the Competitive Ratio of the Online OVSF Code Assignment Problem
Online OVSF code assignment has an important application to wireless communications. Recently, this problem was formally modeled as an online problem, and performances of online algorithms have been analyzed by the competitive analysis. The previous best
Shuichi Miyazaki, Kazuya Okamoto
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

