Results 81 to 90 of about 133,544 (263)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Estimación de un modelo econométrico para determinar el efecto de acciones de marketing en ventas de productos de cuidado personal en Colombia // Panel Analysis to Determine the Effect of Marketing Actions on Sales of Personal Care Products

Revista de Métodos Cuantitativos para la Economía y la Empresa, 2016
Este estudio tiene el objetivo de mostrar a los profesionales del área del marketing cómo se pueden emplear modelos econométricos de panel para realizar un análisis de las acciones de marketing.
Ana M. Arboleda, Julio C. Alonso
doaj  

Individual chronobiological regularity in track-and-field sprint

Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2018
The purpose of the work: to identify the patterns of individual dynamics of competitive performance in track and field sprint. Material. The study involved a highly qualified athlete (running for short distances, long jumps). Results. In the sinusoidal
Zh.L. Kozina, I.F. Prokopenko, M. Cretu, O.I. Chaika, O.A. Ryepko, A.V. Osiptsov, T.O. Razumenko, M.D. Kudryavtsev, A.O. Polianskyi   +8 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Invariance of Competition Outcomes in Hypergraph Competitive Dynamics

CoRR
Winner-take-all (WTA)--type selection is a fundamental mechanism in networked competition, yet its dependence on higher-order interactions remains insufficiently understood. We study a Lotka--Volterra competitive dynamics on higher-order networks, where classical pairwise inhibition is augmented by multi-way interaction terms induced by hyperedges of ...
Qi Zhao, Shaoxuan Cui, Baolin Zhang, Junwei Du, Yuanshi Zheng   +4 more
openaire   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Global Dynamics of Leslie-Gower Competitive Systems in the Plane

Mathematics, 2019
Global dynamic results are obtained for families of competitive systems of difference equations of the ...
Mustafa R. S. Kulenović, David T. McArdle   +1 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Competitive dynamics underlie cognitive improvements during sleep. [PDF]

Proc Natl Acad Sci U S A, 2021
Chen PC, Niknazar H, Alaynick WA, Whitehurst LN, Mednick SC.   +4 more
europepmc   +1 more source