Results 61 to 70 of about 8,368,158 (298)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Empirical support of the positive impact of an Intranet on communication in the working environment

Communicare, 2022
Organizations of all shapes and sizes have to embrace information technology to survive and thrive in an increasingly competitive environment. Consequently, the level of penetration and sophistication of information technology is growing rapidly, and ...
Awie Leonard
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Analysis of competitiveness and competitive advantages in today's market conditions

Менеджмент та підприємництво: тренди розвитку, 2020
The article is devoted to the issues of competitiveness analysis, by which it is possible to evaluate the competitive advantages and disadvantages and to build a strong competitive strategy. The purpose of the article is to research, analyze and identify
Tetiana Pavliuk, Veronika Noda
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Analysis of Temporary Employment Company Business Environment

Socialiniai Tyrimai, 2019
The relevance of the research. The emergence of temporary employment as an atypical form of work organization has become a relevant topic in the research of human resource management processes.
Erika Meškienė, Teodoras Tamošiūnas   +1 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

ASPECTS REGARDING FUNCTIONAL STRATEGIES IN ROMANIAN ORGANIZATIONS

Studies and Scientific Researches: Economics Edition, 2022
This paper is a theoretical approach of the importance of functional strategies use by organizations in order to reach set targets. Functional strategies are closely linked to the changing competitive environment.
Nicoleta Ciucescu, Costel Ceocea, Ovidiu-Leonard Turcu, Andreea Feraru-Prepeliță, Raluca-Alexandra Ceocea   +4 more
doaj  

Systems, Engineering Environments, and Competitions

AI Magazine, 2016
The goal of this article is threefold. First, we trace the history of the development of answer set solvers, by accounting for more than a dozen of them. Second, we discuss development tools and environments that facilitate the use of answer set programming technology in practical applications.
Lierler Yuliya, Maratea Marco, Ricca Francesco   +2 more
openaire   +3 more sources