Results 51 to 60 of about 1,608,481 (312)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

STRENGTHENING OF A FIRM COMPETITIVENESS THROUGH INDUSTRIAL POLICY: A LITERATURE REVIEW

open access: yesЭкономика: стратегия и практика, 2019
The aim of this paper is evaluation different studies related to the industrial policy and its capabilities to increase competitive power of domestic companies, highlighting factors that affect results of such policy and performance of firms.
A. M. Seitkaziyeva   +2 more
doaj  

The Competitive Situation of the Cheminformatics Industry Based on Porter’s Model in Iran

open access: yesSAGE Open, 2022
The purpose of this study was to analyze the competitive situation of the cheminformatics industry using Porter’s competitive model and to determine the priority and weight of each competitive force in this industry.
Asefeh Asemi, Adeleh Asemi, Andrea Ko
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

MAZ technology and competitive power

open access: yesЛитьë и металлургия, 2000
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D. M. Kukuj
doaj  

Budget Allocation in a Competitive Communication Spectrum Economy

open access: yesEURASIP Journal on Advances in Signal Processing, 2009
This study discusses how to adjust “monetary budget” to meet each user's physical power demand, or balance all individual utilities in a competitive “spectrum market” of a communication system.
Ming-Hua Lin, Jung-Fa Tsai, Yinyu Ye
doaj   +1 more source

Bank Competition in India: Some New Evidence Using Risk-Adjusted Lerner Index Approach

open access: yesRisks, 2019
Banks in India have been gone through structural changes in the last three decades. The prices that bank charge depend on the competitive levels in the banking sector and the risk the assets and liabilities carry in banks’ balance sheet.
Rakesh Arrawatia   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Measuring Firm’s Competitiveness [PDF]

open access: yesمطالعات مدیریت راهبردی, 2012
In this research, a model has been developed to measure the firm’s competitive power. The developed model is based on Porter's competitive model and using analytic network process and fuzzy logic techniques. The five forces of Porter’s industry structure
B. Ranjbarian   +2 more
doaj  

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