Results 51 to 60 of about 219,505 (253)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Empresas de revestimento cerâmico e suas estratégias competitivas e de produção Firms of ceramic tiles and its competitive and manufacturing strategies

Gestão & Produção, 2001
Neste trabalho identificamos e discutimos as estratégias competitivas e de produção adotadas por doze empresas da indústria brasileira de cerâmica para revestimento.
Edemilson Nogueira, Alceu Gomes Alves Filho, Ana Lúcia Vitale Torkomian   +2 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Relationship between competitive strategies and innovation

Ciencias Administrativas Teoría y Praxis, 2018
By adopting innovation firms intend to respond   to  environmental  changes   either by  introducing  new products  (differentiation strategy) or by increasing operational efficiency (cost leadership strategy), in both cases companies attempt to improve ...
Claudia Ramos-Garza, Olivia Villalba–Moreno, Leticia Ramos-Garza   +2 more
doaj  

Unidades estratégicas de negócios: uma ferramenta para gestão competitiva de empresas Strategic business units: a tool for the competitive management

Gestão & Produção, 1997
Este artigo tem por objetivo discutir e apresentar algumas considerações acerca das vantagens e implicações da utilização do conceito de UEN - Unidade Estratégica de Negócios, na gestão de empresas, de modo geral.
José Paulo Alves Fusco
doaj   +1 more source

Competitive strategy, development zone policy and firm growth: Empirical evidence from China. [PDF]

PLoS One, 2023
Ye K, Li Y, Wu P, Ye Z.
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Introdução de catalisadores metalocênicos como estratégia competitiva da indústria de termoplásticos The introduction of metallocene catalysts as a competitive strategy of the thermoplastic industry

Polímeros, 1997
Recentes inovações tecnológicas no setor de polímeros levaram a novos catalisadores que poderão mudar a estrutura de toda a indústria. É feita uma análise das estratégias competitivas adotadas pelas empresas do setor e do impacto que a adoção dos ...
Francisco A. Ribeiro Fº, Maria José S. Ferreira Netto, Carlos A. Hemais   +2 more
doaj   +1 more source

Sustaining the potential for cooperation as female competitive strategy. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2023
Cassar A, Rigdon M.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source