Results 51 to 60 of about 1,124,396 (289)
Gender and Age Patterns in NSGA Swim Competitions
Journal of Aging Research, 2022 We estimate two common nonlinear models (quadratic and semilog) and one new model (exponential) of the time-age relationship in 500-yard freestyle swim times in the U.S. National Senior Games (ages 50 and up) in six biennial NSGA competitions (2009, 2011, 2013, 2015, 2017, and 2019) for 468 men and 587 women. We use OLS and quantile regression (25%, 50%
David P. Doane +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The development of free-swimming in Xenopus laevis larvae [PDF]
, 2013 In Xenopus laevis frog tadpoles, highly self-motive, free-swimming behaviour emerges at the onset of feeding. This is in contrast to the earlier post-hatched larval form, which is capable of escape swimming when stimulated, but normally lies dormant.
Scott, Nicholas W.
core +2 more sources
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Aspects of the respiratory metabolism of juvenile rainbow trout (Oncorhynchus mykiss) at sustained swimming speeds [PDF]
, 1993 Bibliography: leaves 98-111.A detailed description of the design of an apparatus suitable for investigations into the respiratory physiology of small nektonic organisms at various swimming speeds is presented. Juvenile rainbow trout (Oncorhynchus mykiss)
Durholtz, Deon
core +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
The thermal dependence of swimming and muscle physiology in temperate and Antarctic scallops [PDF]
, 2015 Swimming is important to the ecology of many species of scallop but the effects of temperature upon swimming are not clear. The ecology and natural history of scallops is introduced followed by a description of the state of current ...
Bailey, David Mark
core +2 more sources
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Keeping swimmers swimming: The capacity of swimming clubs [PDF]
, 2008 The Department of Culture Media and Sport has signed a Public Service Agreement (PSA) with Sport England with explicit targets to increase participation in sport and active recreation.
Robinson, Leigh
core
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source