Results 31 to 40 of about 1,092,439 (295)

Environmental effectiveness of GAEC cross-compliance Standard 4.1 (b, c) ‘Protection of permanent pasture land’ and economic evaluation of the competitiveness gap for farmers

Italian Journal of Agronomy, 2015
The paper presents the main results of the monitoring on the effectiveness of the cross-compliance Standard 4.1 ‘Permanent pasture protection: lett. b, c’ carried out in two case studies within the project MO.NA.CO.
Mauro Salis, Lucia Sepe, Rosa Francaviglia, Marco Fedrizzi, Paolo Bazzoffi, Salvatore Claps, Maurizio Pitzalis, Michele Lilliu, Paola Ruda, Emilio Sabia, Annarita Bruno, Domenico Rufrano, Maria Teresa Dell'Abate, Alberto Alianello, Marco Veloccia, Olimpia Masetti, Gianluca Renzi, Roberto Fanigliulo, Mauro Pagano, Giulio Sperandio, Mirko Guerrieri, Daniele Puri, Antonio Melchiorre Carroni   +22 more
doaj   +1 more source

Competitive IPOs [PDF]

European Financial Management, 2008
Abstract Competition between investment banks for lead underwriter mandates in IPOs is fierce, but having committed to a particular bank, the power of the issuer is greatly reduced. Although information revelation theories justify giving the underwriters influence over pricing and allocation, this creates the potential for conflicts of interest.
Jenkinson, Tim, Jones, Howard
openaire   +5 more sources

Environmental effectiveness of the cross compliance Standard 4.6 ‘Minimum livestock stocking rates and/or appropriate regimens’

Italian Journal of Agronomy, 2015
The paper presents the main results of the monitoring on the effectiveness of the cross compliance Standard 4.6 ‘Minimum livestock stocking rates and/or appropriate regimes’ carried out in two case studies within the project MO.NA.CO: sheep grazing in ...
Lucia Sepe, Mauro Salis, Rosa Francaviglia, Marco Fedrizzi, Antonio Melchiorre Carroni, Emilio Sabia, Annarita Bruno, Domenico Rufrano, Paola Ruda, Maria Teresa Dell'Abate, Alberto Alianello, Marco Veloccia, Olimpia Masetti, Gianluca Renzi, Roberto Fanigliulo, Mauro Pagano, Giulio Sperandio, Mirko Guerrieri, Daniele Puri, Salvatore Claps   +19 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The influence of late-stage pupal irradiation and increased irradiated:un-irradiated male ratio on mating competitiveness of the malaria mosquito Anopheles arabiensis Patton [PDF]

, 2009
Competitiveness of released males in genetic control programmes is of critical importance. In this paper, we explored two scenarios to compensate for the loss of mating competitiveness after pupal stage irradiation in males of the malaria mosquito ...
Helinski, M., Knols, B.G.J.
core   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source