Results 101 to 110 of about 731,458 (247)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
E-Spania, 2018 La compilation des Navigationi et viaggi est systématiquement citée dans les ouvrages traitant de l’émergence de l’histoire globale, du fait de l’échelle adoptée ou de la variété des sources utilisées par Ramusio pour mettre à jour l’image du monde au ...
Fiona Lejosne
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Alfonso X, Bernardo de Brihuega y la General estoria
Atalaya, 2018 This article offers a general presentation of the hagiographical production by Bernardo de Brihuega, particularly its Castilian version, giving an account of the most recent research.
Francisco Bautista
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
A2J Summit Collection Contributors [PDF]
, 2019 A compilation of biographies for the authors and participants in this ...
Udell, David
core +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Cadernos de Fraseoloxía Galega, 2007 Nesta recadádiva recóllense e explícanse 108 fórmulas (sen contar variantes) que se empregan na actualidade en moi variados puntos do país galego.
https://www.cirp.gal/pub/docs/cfg/cfg09_13.pdf
doaj
Research on the Standardization of Drug Test Data
MATEC Web of Conferences, 2017 In order to solve the problems that test data of the drug control institution is not standardized and low quality, the data exchange and information sharing are realized, the data value is mined and the information level is improved.
Lin Weiqiang +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source