Results 71 to 80 of about 97,953 (247)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Alfonso X, Bernardo de Brihuega y la General estoria

open access: yesAtalaya, 2018
This article offers a general presentation of the hagiographical production by Bernardo de Brihuega, particularly its Castilian version, giving an account of the most recent research.
Francisco Bautista
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

108 fórmulas galegas [PDF]

open access: yesCadernos de Fraseoloxía Galega, 2007
Nesta recadádiva recóllense e explícanse 108 fórmulas (sen contar variantes) que se empregan na actualidade en moi variados puntos do país galego.
https://www.cirp.gal/pub/docs/cfg/cfg09_13.pdf
doaj  

Research on the Standardization of Drug Test Data

open access: yesMATEC Web of Conferences, 2017
In order to solve the problems that test data of the drug control institution is not standardized and low quality, the data exchange and information sharing are realized, the data value is mined and the information level is improved.
Lin Weiqiang   +5 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Zusammenstellung der Spinnenfamilien Mitteleuropas, mit Auflistung bemerkenswerter Benennungen, Schreibweisen und Zuordnungen von Arten und Gattungen nach Platnick (1997), mit Anmerkungen und Ergänzungen

open access: yesArachnologische Mitteilungen, 1998
List of the Central European families of spiders, with a list of remarkable nomenclatural changes of species and genera by Platnick (1997), with remarks and additions.
Blick, Theo
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

اسلامی قانون بین الاقوام: تدوین ومآخذکا تاریخی و تحقیقی جائزہ

open access: yesپاکستان جرنل آف اسلامک فلاسفی
Islamic international law is a codified system of law that governs the principles of states, nations and international relations in light of Islamic Sharia.
Dr. Nazia Zaman
doaj  

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