Results 141 to 150 of about 37,010 (319)

UCP2 Upregulates ACSL3 to Enhance Lipid Droplet Release from Acinar Cells and Modulates the Sirt1/Smad3 Pathway to Promote Macrophage‐to‐Myofibroblast Transition in Chronic Pancreatitis

Advanced Science, EarlyView.
These findings suggest that UCP2 promotes LD formation and release in acinar cells by upregulating ACSL3 expression. This alteration in the local lipid metabolic environment indirectly drives the MMT process. Additionally, UCP2 may regulate the acetylation of Smad3 through Sirt1, enhancing its nuclear activity and activating the TGF‐β/ Smad3 signaling ...
Kunpeng Wang, Lilong Zhang, Beiying Deng, Wanrong Jiang, Tianrui Kuang, Chen Chen, Kailiang Zhao, Qiao Shi, Jun He, Weixing Wang   +9 more
wiley   +1 more source

GAHLS: an optimized graph analytics based high level synthesis framework. [PDF]

Sci Rep, 2023
Xiao Y, Nazarian S, Bogdan P.
europepmc   +1 more source

Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis

Advanced Science, EarlyView.
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao, Ruiyan Ma, Shuai Hao, Xuxin Tan, Xue Zeng, Rui Song, Bing Chen, Zhezhe Cao, Wei Shen, Zhenchun Luo, Jianfeng Huang, He Huang, Liangming Liu, Chenyang Duan   +13 more
wiley   +1 more source

Evaluating statistical consistency for the ocean component of earth system models using physics informed convolutional autoencoder. [PDF]

Sci Rep
Yu Y, Zhang S, Fu H, Chen D, Jin Y, Gao Y, Lin X, Liu Z, Lv X, Fei Y, Wang K.   +10 more
europepmc   +1 more source

BinBench: a benchmark for x64 portable operating system interface binary function representations. [PDF]

PeerJ Comput Sci, 2023
Console F, D'Aquanno G, Di Luna GA, Querzoni L.   +3 more
europepmc   +1 more source

Flora boreali-Americana, or, The botany of the northern parts of British America compiled principally from the plants collected by Dr. Richardson & Mr. Drummond on the late northern expeditions, under command of Captain Sir John Franklin, R.N. to which are added (by permission of the Horticultural Society of London) those of Mr. Douglas from north west America and other naturalists

William Jackson Hooker
openalex   +2 more sources

Human iPSC‐Derived Mononuclear Phagocytes Improve Cognition and Neural Health across Multiple Mouse Models of Aging and Alzheimer's Disease

Advanced Science, EarlyView.
Short‐term intravenous treatments with iPSC‐derived mononuclear phagocytes (iMPs) improve cognitive decline and neural health in two mouse models of aging and in the 5xFAD mouse model of Alzheimer's disease. iMPs reduce levels of serum amyloid proteins that increase in aging and improve the health of hippocampal microglia and mossy cells.
V. Alexandra Moser, Luz Jovita Dimas‐Harms, Rachel M. Lipman, Jake Inzalaco, Shaughn Bell, Michelle Alcantara, Erikha Valenzuela, George Lawless, Simion Kreimer, Sarah J. Parker, Helen S. Goodridge, Clive N. Svendsen   +11 more
wiley   +1 more source

Graph neural networks with configuration cross-attention for tensor compilers. [PDF]

Front Artif Intell
Khizbullin D, de Andrade ER, Nguyen TH, Ferreira MP, Pugh DR.   +4 more
europepmc   +1 more source

Sylva telluriana. Mantis. synopt. New genera and species of trees and shrubs of North America, and other regions of the earth, omitted or mistaken by the botanical authors and compilers, or not properly classified, no reduced by their natural affinities to the proper natural orders and tribes. By C.S. Rafinesque. Being a supplement to the Flora telluriana

C. S. Rafinesque, C. S. Rafinesque
openalex   +2 more sources

XIII. A Revised List of British Trichoptera, brought down to date; compiled with especial regard to the ‘Catalogue of British Neuroptera,‘ published by the Society in 1870

, 1882
Robert M‘Lachlan
openalex   +2 more sources