Results 211 to 220 of about 230,052 (302)

A deep-learning-based consistency test approach for Earth system models on HPC systems. [PDF]

iScience
Yu Y, Zhang S, Fu H, Chen D, Gao Y, Lin X, Liu Z, Lv X.   +7 more
europepmc   +1 more source

5‐Hydroxymethylcytosine Dynamics Reveals Coordinated Reprogramming of Parental Genomes and X Chromosome Dosage Balance in Mouse SCNT Embryos

Advanced Science, EarlyView.
Genome‐wide, high‐resolution profiling of hydroxymethylation in mouse SCNT embryos reveals a transient, allele‐symmetric 5hmC reprogramming pattern distinct from natural embryos, with X‐chromosomes and imprinting control regions resistant to proper remodeling.
Zeming Xiang, Rui Yan, Jing Guo, Mengyao Wang, Xin Cheng, Fan Zhang, Tianzi Guo, Xin Long, Fan Guo, Dan Liang   +9 more
wiley   +1 more source

Exploring code portability solutions for HEP with a particle tracking test code. [PDF]

Front Big Data
Ather H, Berkman S, Cerati G, Kortelainen MJ, Kwok KHM, Lantz S, Lee S, Norris B, Reid M, Reinsvold Hall A, Riley D, Strelchenko A, Wang C.   +12 more
europepmc   +1 more source

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

Optimizing software engineering English translation using an enhanced Grey Wolf Optimization with self-attention and Bi-LSTM model. [PDF]

Sci Rep
Yuan F, Liu Y, Ju Y, Abdalla AN.
europepmc   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Decoding large language models for radiology: strategies for fine-tuning and prompt engineering. [PDF]

Radiol Adv
Vahdati S, Mahmoudi E, Ganjizadeh A, Chao C, Erickson BJ.   +4 more
europepmc   +1 more source

Floey, an intermediate language for optimizing compilers

, 2008
N Tang
openalex   +2 more sources

Ferroptosis‐Mediated Hippocampal Neuronal Loss Post‐mTBI: Chromatin Accessibility Profiling and Single‐Nucleus Transcriptomics

Advanced Science, EarlyView.
Hippocampal single ‐nucleus transcriptomes and chromatin accessibility after mild traumatic brain injury reveal dentate granule neuron vulnerability driven by ferroptosis. The c‐Jun–Tmsb4x–Slc2a2 axis modulates lipid peroxidation and iron dysregulation.
Manrui Li, Qiuyun Yang, Shengqiu Qu, Yang Chen, Yang Shen, Yang Xu, Xilong Lin, Yihan Sun, Ying Chen, Meili Lv, Lin Zhang, Zengqiang Yuan, Weibo Liang, Xiameng Chen   +13 more
wiley   +1 more source

Real-time signal processing enabled by fused networks on a memristor-based system on a chip. [PDF]

Sci Adv
Wang Z, Song W, Wang T, Wang Z, Xu Y, Rao M, Cai F, Yin W, Chen MS, Ge N, Collins M, Bai K, Ganguli S, Page MR, Wu Q, Katehi L, Xia Q, Hu M, Yang JJ.   +18 more
europepmc   +1 more source