Results 291 to 300 of about 223,297 (353)

SCORCH2: A Generalized Heterogeneous Consensus Model for High‐Enrichment Interaction‐Based Virtual Screening

Advanced Science, EarlyView.
Researchers developed SCORCH2, an advanced machine‐learning scoring function for virtual screening that combines two complementary XGBoost models to re‐evaluate protein‐ligand binding plausibility. The method demonstrates superior performance on standard benchmarks, shows excellent generalization to previously unseen protein targets, and provides ...
Lin Chen, Vincent Blay, Pedro J. Ballester, Douglas R. Houston   +3 more
wiley   +1 more source

A dataset of windows system binaries and similarity digests for enhanced forensic analysis. [PDF]

Data Brief
Huici D, Rodríguez RJ.
europepmc   +1 more source

Enhancing Spatial Transcriptomics via Spatially Constrained Matrix Decomposition with EDGES

Advanced Science, EarlyView.
Imaging‐based spatial transcriptomics technologies are currently limited by their restricted gene detection capacity and low measurement accuracy. Moreover, the insufficient integration of spatial context and single‐cell reference data poses a significant challenge for comprehensive data analysis.
Jinyue Zhao, Jiating Yu, Yuqing Cao, Fan Yuan, Ling‐Yun Wu, Duanchen Sun   +5 more
wiley   +1 more source

GBsim: A Robust GCN-BERT Approach for Cross-Architecture Binary Code Similarity Analysis. [PDF]

Entropy (Basel)
Du J, Wei Q, Wang Y, Bai X.
europepmc   +1 more source

Carbon Catalyst Supports for Pt‐Based Polymer Electrolyte Membrane Fuel Cells: Porosity, Graphitization, and Chemical Modifications

Advanced Science, EarlyView.
This review explores recent advancements in understanding the influence of carbon support properties on the cathode performance of proton exchange membrane fuel cells. It proposes a set of properties deemed critical for the development of next‐generation carbon supports for the oxygen reduction reaction in fuel cells.
Camille Roiron, Alessio Cosenza, Giovanni Ferro, Jiazhe Loki Chen, Hanson Wang, Plamen Atanassov   +5 more
wiley   +1 more source

Benchmarking the performance of quantum computing software for quantum circuit creation, manipulation and compilation. [PDF]

Nat Comput Sci
Nation PD, Saki AA, Brandhofer S, Bello L, Garion S, Treinish M, Javadi-Abhari A.   +6 more
europepmc   +1 more source

From Knitting Technology to Robotics: Untethered Thermally Actuated Textile Exoskeleton for Dexterity Applications

Advanced Science, EarlyView.
A textile‐based exoskeleton glove with integrated thermally driven actuators achieves rapid, low‐power response for dexterous motion. Utilizing advanced knitting methods, embedded heaters, and hybrid yarn sensors, the glove bends in a segmented fashion under 12 s at only 10.8 W and 48 °C.
Ibrahim Adel Khamis Ahmed, Munire Sibel Cetin, Kadir Ozlem, Asli Tuncay Atalay, Gökhan Ince, Ozgur Atalay   +5 more
wiley   +1 more source

ASIP Performance Enhancement by Hazard Control through Scoreboard. [PDF]

Micromachines (Basel)
Zhou X, Man Y, Hao P, Chen W, Yang B, Ding B, Liu D.   +6 more
europepmc   +1 more source

Aging as a Loss of Goal‐Directedness: An Evolutionary Simulation and Analysis Unifying Regeneration with Anatomical Rejuvenation

Advanced Science, EarlyView.
The paper proposes that the root cause of aging is the loss of anatomical goal‐directedness after development. Using evolutionary neural cellular automata simulations, the authors show that after the organism has reached its developmental homeostatic setpoint (the adult morphology), the absence of target state to pursue leads to a drifting anatomical ...
Léo Pio‐Lopez, Benedikt Hartl, Michael Levin   +2 more
wiley   +1 more source

Targeting Mast Cell Activation and MIF‐Mediated Remodelling Enhances Chemotherapy Response in Pancreatic Cancer

Advanced Science, EarlyView.
Neoadjuvant gemcitabine plus nab‐paclitaxel (AG) reprograms pancreatic ductal adenocarcinoma by shifting malignant cells toward a classical phenotype and remodeling the tumor microenvironment. Despite enhancing cytotoxic NKT cells, AG activates tumor‐associated mast cells (TAMCs) and inflammatory CAFs through MIF signaling.
Libo Wang, Guangcong Shen, Guanpeng Xie, Zekun Li, Xiaoqing Ma, Mengyu Li, Ziyun Liu, Yadi Wang, Zongjing Lv, Qingxiao Fang, Huihui Sun, Ningning Zhao, Chao Yang, Tianxing Zhou, Yongjie Xie, Jun Yu, Jihui Hao   +16 more
wiley   +1 more source