Results 41 to 50 of about 45,889 (314)

Compiling language definitions [PDF]

open access: yesACM Transactions on Programming Languages and Systems, 2002
The ASF+SDF Meta-Environment is an interactive language development environment whose main application areas are definition and implementation of domain-specific languages, generation of program analysis and transformation tools, and production of software renovation tools.
Mark van den Brand   +3 more
openaire   +4 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

3D Tiled Code Generation for Nussinov’s Algorithm

open access: yesApplied Sciences, 2022
Current state-of-the-art parallel codes used to calculate the maximum number of pairs for a given RNA sequence by means of Nussinov’s algorithm do not allow for achieving speedup close up to the number of the processors used for execution of those codes ...
Włodzimierz Bielecki   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

arXiv/arxiv-compiler: arXiv compiler service v0.1-alpha

open access: yes, 2019
Release notes - arXiv-NG - Version compiler-0.1-alpha <p><h2> New Feature </h2></p> <ul> <li>[<a href='https://arxiv-org.atlassian.net/browse/ARXIVNG-1642'>ARXIVNG-1642</a>] - Compiler ...
David Fielding   +3 more
core   +1 more source

Power Usage Monitoring Simulator for Estimating Usage Tariffs and Carbon Emission Levels at STO Bogor Based on IoT

open access: yesCompiler
In this modern era, the efficiency of electricity usage has become one of the main concerns in the efforts toward sustainable energy management. The limitations in monitoring electricity usage have become a challenge for technicians, resulting in ...
Nurwijayanti Kusumaningrum, Rizky Syafdi
doaj   +1 more source

Supporting Separate Compilation in a Defunctionalizing Compiler.

open access: yesOpenAccess Series in Informatics, 2013
Defunctionalization is generally considered a whole-program transformation and thus incompatible with separate compilation. In this paper, we formalize a modular variant of defunctionalization which can support separate compilation. Our technique allows modules in a Haskell-like language to be separately defunctionalized and compiled, then linked ...
Georgios Fourtounis 0001   +1 more
openaire   +3 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Baseline Evaluation of Backpropagation Artificial Neural Network for Visual Image-Based Vehicle Type Classification

open access: yesCompiler
The increasing number of vehicles in urban areas requires technology-based solutions for efficient transportation management. This study proposes a vehicle classification model using Artificial Neural Networks (ANN) with the backpropagation algorithm ...
Rika Harman, Imam Riadi, Abdul Fadlil
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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