Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation
Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy +16 more
wiley +1 more source
Injury as a stressor in 67 first year contemporary dance students: a longitudinal cohort study. [PDF]
Kaufmann JE +4 more
europepmc +1 more source
Cognitive Trajectories from Preclinical Alzheimer's Disease to Dementia
A continuous, multi‐domain characterization of cognitive decline across the Alzheimer's disease spectrum identifies when individual cognitive measures become abnormal. Episodic memory declines first, followed by executive function, language, processing speed, and visuospatial abilities, supporting improved clinical interpretation and optimized endpoint
Fredrik Öhman +3 more
wiley +1 more source
Suicidal Ideation in Pediatric Orthopaedic Patients. [PDF]
Herge WM +7 more
europepmc +1 more source
Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak +9 more
wiley +1 more source
On the Design of a Sign Language Corpus of Medical Terms for Automatic Translation Systems: Mixed Methods Approach. [PDF]
Marcolino MS +3 more
europepmc +1 more source
Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li +22 more
wiley +1 more source
Early Intensive Care Unit Length of Stay Prediction on MIMIC-IV: A Dual Approach With Clinical Features and Textual Notes. [PDF]
She Y, Wood-Doughty Z.
europepmc +1 more source
Report on an investigation into complaint no 09 017 510 about Kent County Council and complaint no 09 017 512 about Dover District Council, 31 July 2012 [PDF]
Seex, Anne
core
Neural Fields for Highly Accelerated 2D Cine Phase Contrast MRI
ABSTRACT 2D cine phase contrast (CPC) MRI provides quantitative information on blood velocity and flow within the human vasculature. However, data acquisition is time‐consuming, motivating the reconstruction of the velocity field from undersampled measurements to reduce scan times. In this work, neural fields are proposed as a continuous spatiotemporal
Pablo Arratia +7 more
wiley +1 more source

