Results 311 to 320 of about 1,441,098 (322)

The treatment of autoimmune hemolytic anemia with complement inhibitor iptacopan: a case report. [PDF]

Front Med (Lausanne)
Li X, Zhou M, Ma S, Wang R, Zhao C, Chen C.   +5 more
europepmc   +1 more source

Brain-penetrant complement inhibition mitigates neurodegeneration in an Alzheimer's disease mouse model. [PDF]

Brain
Zelek WM, Bevan RJ, Nimmo J, Dewilde M, De Strooper B, Morgan BP.   +5 more
europepmc   +1 more source

Plasma Exosomal-Derived SERPINA1 and GNAI2 Downregulation as Potential Diagnostic Biomarkers of Kawasaki Disease with Coronary Artery Aneurysms. [PDF]

Int J Mol Sci
Zheng Y, Bai B, Wei Z, Zhang M, Zhang Q, Li X.   +5 more
europepmc   +1 more source

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of ALXN1820 (Tarperprumig) in Healthy Adults: Results of a Phase I Study. [PDF]

Clin Transl Sci
Sandhu A, Shen T, Herrero PM, Yuan CX, Qureshi S, Jiang X, Sheng Y, Gasteyger C, Dai Y.   +8 more
europepmc   +1 more source

Properdin deficiency associated with systemic meningococcal disease due to a novel p.Cys337Arg pathogenic variant

Genes and Diseases
Laura González-Sánchez, Ana Mei Agudo, Anne Van Den Rym, María Isabel Begiristain, Alazne Saizar, Rebeca Pérez de Diego, Pilar Nozal, Alberto López-Lera, Margarita López-Trascasa, Fernando Corvillo   +9 more
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The Protein Kinase Complement of the Human Genome

Science, 2002
We have catalogued the protein kinase complement of the human genome (the “kinome”) using public and proprietary genomic, complementary DNA, and expressed sequence tag (EST) sequences.
G. Manning, D. Whyte, R. Martinez, T. Hunter, S. Sudarsanam   +4 more
semanticscholar   +1 more source

Microglia mediate forgetting via complement-dependent synaptic elimination

Science, 2020
Microglia modulate memories Synaptic reorganization and circuit rewiring leads to loss or weakening of connections between neurons and may result in the erasure of previously formed memories. Microglia eliminate excessive synapses in the developing brain
Chao Wang, Huimin Yue, Zhechun Hu, Yuwen Shen, Jiao Ma, Jie Li, Xiao-Dong Wang, Liang Wang, Binggui Sun, Peng Shi, Lang Wang, Yan Gu   +11 more
semanticscholar   +1 more source

The Minimal Gene Complement of Mycoplasma genitalium

Science, 1995
The complete nucleotide sequence (580,070 base pairs) of the Mycoplasma genitalium genome, the smallest known genome of any free-living organism, has been determined by whole-genome random sequencing and assembly.
C. Fraser, J. Gocayne, O. White, M. Adams, R. Clayton, R. Fleischmann, C. Bult, A. Kerlavage, G. Sutton, J. M. Kelley, J. Fritchman, J. Weidman, Keith V. Small, M. Sandusky, J. Fuhrmann, David Nguyen, T. Utterback, D. Saudek, C. Phillips, J. Merrick, J. Tomb, B. Dougherty, K. Bott, P. Hu, T. Lucier, S. Peterson, Hamilton O. Smith, C. Hutchison, J. Venter   +28 more
semanticscholar   +1 more source

Complement Factor H Polymorphism and Age-Related Macular Degeneration

Science, 2005
Age-related macular degeneration (AMD) is a common, late-onset, and complex trait with multiple risk factors. Concentrating on a region harboring a locus for AMD on 1q25-31, the ARMD1 locus, we tested single-nucleotide polymorphisms for association with ...
A. Edwards, R. Ritter, K. Abel, A. Manning, Carolien I. M. Panhuysen, L. Farrer   +5 more
semanticscholar   +1 more source

Complement. First of two parts.

New England Journal of Medicine, 2001
M. Walport
semanticscholar   +1 more source