Results 311 to 320 of about 2,568,874 (328)

Structure and activation of complement components C2 and Factor B

Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1984
The activation of complement is initiated by two independent pathways. Each leads to the formation of a complex protease, C3 convertase, with equivalent specificity and function but different composition. The convertase derived from the classical pathway is composed of complement components C4 and C2 while that from the alternative pathway consists of ...
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GENOMIC ANALYSIS OF THE F SUBTYPES OF HUMAN COMPLEMENT FACTOR B

International Journal of Immunogenetics, 1994
SUMMARYFactor B of human complement is encoded within the Major Histocompatibility Complex (MHC) and is polymorphic, with up to 30 alleles defined by electrophoretic mobility. One of the most common alleles, BF*F, is subdivided into the FA and FB subtypes, which differ at the gene level by non‐synonymous base substitutions in the seventh codon. We have
I. Jahn, G. Hauptmann, H. Schröder, C. Darke, G. Geserick, M. Thomas, J. E. Mejéa   +6 more
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A New Complement Factor B Variant (BF S075) in Japanese

Human Heredity, 1990
A new slow-moving variant of the complement factor B, named BF S075, was found in a Japanese patient with cerebral thrombosis and urticaria. The variant was inherited in a codominant manner. The protein concentration and functional hemolytic activity of the complement factor B in the patient's serum were within normal limits.
Takaaki Shinomiya, Ikuro Maruyama, Satoshi Takenaga, Hiroaki Nishimukai, Hajime Kitamura, Kenji Mizutani   +5 more
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Duplication of the MHC-linked Xenopus complement factor B gene

Immunogenetics, 1995
We have previously reported the molecular cloning of the mammalian major histocompatibility complex (MHC) class III gene, complement factor B (Bf) from Xenopus laevis, and linkage of the gene to the frog MHC. Here, we estimated the copy number of the Xenopus Bf gene by genomic Southern blotting analysis and demonstrated that Xenopus laevis has two ...
Makoto Sasaki, Luisa Salter-Cid, Chisato Namikawa, Martin F. Flajnik, Yoichi Kato, Masaru Nonaka   +5 more
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Identification of human complement factor B as a novel biomarker candidate for pancreatic ductal adenocarcinoma.

Journal of Proteome Research, 2014
Min Jung Lee, Keun Na, Seul‐Ki Jeong, Jong-Sun Lim, S. Kim, Min‐Ji Lee, S. Song, Hoguen Kim, W. Hancock, Y. Paik   +9 more
semanticscholar   +1 more source

Complement factor B

1998
Tak W. Mak, Josef Penninger, John Roder, Janet Rossant, Mary Saunders   +4 more
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A Complement Factor B Mutation in a Large Kindred with Atypical Hemolytic Uremic Syndrome

Journal of Clinical Immunology, 2014
M. Funato, O. Uemura, K. Ushijima, H. Ohnishi, K. Orii, Zenichiro Kato, Satoshi Yamakawa, Takuhito Nagai, O. Ohara, H. Kaneko, N. Kondo   +10 more
semanticscholar   +1 more source

Complement Factor B Polymorphism and the Phenotype of Early Age-related Macular Degeneration

Ophthalmic Genetics, 2014
I. Mantel, A. Ambresin, L. Moetteli, I. Droz, R. Roduit, F. Munier, D. Schorderet   +6 more
semanticscholar   +1 more source

Eculizumab therapy for atypical haemolytic uraemic syndrome due to a gain-of-function mutation of complement factor B

Pediatric nephrology (Berlin, West), 2013
R. Gilbert, D. Fowler, E. Angus, S. Hardy, Louise Stanley, T. Goodship   +5 more
semanticscholar   +1 more source

Molecular cloning of lamprey complement factor B

Molecular Immunology, 1993
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