Results 311 to 320 of about 484,151 (372)

C1q+ Macrophage–Tumor Cell Interaction Promoted Tumorigenesis via GPR17/PI3K/AKT Pathway Induced DNA Hypermethylation in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
In the TME of NPC, C1q secreted by C1q+ TAMs interacted with GPR17 to activate PI3K/AKT signaling through strengthening GPR17 coupling PI3K and increasing calcium levels in tumor cells. The activated PI3K/AKT signaling further induces DNA hypermethylation to promote the malignancy and stemness of tumor cells.
Yunzhi Liu, Cuicui Huang, Min Luo, Wenfu Lu, Baifeng Zhang, Lu Bai, Shuyue Zheng, Yanan Tan, Shanshan Li, Huali Wang, Lanqi Gong, Xinyuan Guan   +11 more
wiley   +1 more source

Conjugation Chemistry Markedly Impacts Toxicity and Biodistribution of Targeted Nanoparticles, Mediated by Complement Activation. [PDF]

Adv Mater
Zaleski MH, Chase LS, Hood ED, Wang Z, Nong J, Espy CL, Zamora ME, Wu J, Morrell LJ, Muzykantov VR, Myerson JW, Brenner JS.   +11 more
europepmc   +1 more source

CeiTEA: Adaptive Hierarchy of Single Cells with Topological Entropy

Advanced Science, EarlyView.
CeiTEA, a novel hierarchical clustering algorithm based on topological entropy, effectively captures complex structures underlying data. By constructing an adaptive multi‐nary partition tree, CeiTEA reveals hierarchical structures and local diversifications, outperforming existing methods in clustering accuracy and consistency and providing the ...
Bowen Tan, Shiying Li, Mengbo Wang, Shuai Cheng Li   +3 more
wiley   +1 more source

Testing for Blastomycosis, Coccidioidomycosis, and Histoplasmosis at a Major Commercial Laboratory, United States, 2019-2024. [PDF]

Open Forum Infect Dis
Benedict K, Williams SL, Smith DJ, Lindsley MD, Lockhart SR, Toda M.   +5 more
europepmc   +1 more source

Recent Advances in Enhancing the Sensitivity of Biosensors Based on Field Effect Transistors

Advanced Electronic Materials, EarlyView.
This paper discusses the methods to enhancing the detection sensitivity of biosensors in three aspects: overcoming the influence of Debye shielding effects, promoting the binding efficiency of analytes and transistor surface, and improving the structures of device.
Yuying Zhou, Tongshi Feng, Yao Li, Xiang Ao, Shengfa Liang, Xiaonan Yang, Lingfei Wang, Xiaoxin Xu, Wenchang Zhang   +8 more
wiley   +1 more source

Fast Feature- and Category-Related Parafoveal Previewing Support Free Visual Exploration. [PDF]

J Neurosci
Fakche C, Hickey C, Jensen O.
europepmc   +1 more source

Toward High‐Performance Electrochemical Energy Storage Systems: A Case Study on Predicting Electrochemical Properties and Inverse Material Design of MXene‐Based Electrode Materials with Automated Machine Learning (AutoML)

Advanced Electronic Materials, EarlyView.
This study demonstrates PyCaret's AutoML framework for predicting the electrochemical and structural properties of MXene‐based electrodes, including intercalation voltage, capacity, and lattice constants. AutoML streamlines workflows, ranks key elemental descriptor, and enables inverse molecular formula prediction based on performance targets.
Berna Alemdag, Görkem Saygili, Matthias Franzreb, Gözde Kabay   +3 more
wiley   +1 more source

Neurovisual Training With Acoustic Feedback: An Innovative Approach for Nystagmus Rehabilitation. [PDF]

Arch Rehabil Res Clin Transl
Antognetti D, Maggiani L, Gabbrielli E, Allegrini L, Dalise S, Chisari C.   +5 more
europepmc   +1 more source

Nonapoptotic caspase-3 guides C1q-dependent synaptic phagocytosis by microglia. [PDF]

Nat Commun
Andoh M, Shinoda N, Taira Y, Araki T, Kasahara Y, Takeuchi H, Miura M, Ikegaya Y, Koyama R.   +8 more
europepmc   +1 more source

Impact of glycemic control on coccidioidomycosis outcomes in patients with underlying diabetes mellitus in central California. [PDF]

Med Mycol
Sivasubramanian G, Fox K, Huynh N, Woodley J, Chan-Golston A, Policepatil S.   +5 more
europepmc   +1 more source