Smart Nanodelivery Systems for Immunometabolic Modulation in Osteoarthritis
Smart nanodelivery systems deliver therapeutic payloads across the cartilage matrix to ensure their sustained accumulation within chondrocytes at sites of injury. By targeting specific molecular targets and signaling pathways, these platforms modulate the pathological synovium‐cartilage axis to restore immunometabolic homeostasis and drive tissue ...
Qirui Zhao +20 more
wiley +1 more source
Allogeneic, Xenogeneic, and Exogenic Hearts for Transplantation. [PDF]
Garry DJ +7 more
europepmc +1 more source
This review highlights non‐thermal extraction technologies for seaweed proteins, emphasizing their mechanisms, impacts on protein structure and functionality, and sustainability potential. Key limitations related to species dependence, extract complexity, and scale‐up are discussed to guide future industrial and biorefinery applications.
Rahat Mahmud +3 more
wiley +1 more source
Immune evasion of multidrug-resistant bacteria: insights from lung innate immune cells and targeted therapies. [PDF]
Xu Y, Gao Y, Li Y, Pan L.
europepmc +1 more source
A New Vista of Opportunity in Diabetes Management: Natural Product‐Based β‐cell Preservation
Preserving functional β‐cells via natural products offers promising strategy for diabetes treatment. ABSTRACT A defining characteristic of diabetes is β‐cell failure, in which β‐cells cannot modulate insulin secretion to compensate for escalating insulin resistance, pushing forward disease development.
Yi‐San Lee +4 more
wiley +1 more source
Complement Inhibition Therapy in Myasthenic Crisis-A Multicentre Retrospective Analysis of 17 Cases From Germany. [PDF]
Gerischer L +24 more
europepmc +1 more source
Pulsed light technology uses short high‐intensity broad‐spectrum flashes (200–1100 nm) to inactivate microbes via DNA damage. It preserves food quality, extends shelf life, and works on liquids, meats, and produce, often combined with other hurdles for enhanced efficacy.
Abdul Mueez Ahmad +4 more
wiley +1 more source
New Analogs of the Compstatin Family of Clinical Complement Inhibitors with Low Picomolar Target Affinity. [PDF]
Vogt SA +12 more
europepmc +1 more source
Dynamic Culture of TDSCs on a Mechanically Biomimetic PCL/COL Flexible Substrate
A mechanically biomimetic PCL/COL flexible substrate with electrospun fibers promoted the alignment and tenogenic differentiation of TDSCs under dynamic stimulation. This platform links structural design to cellular response and offers a promising strategy for tendon tissue engineering.
Changyun Wang +4 more
wiley +1 more source
Real-world effectiveness and safety of eculizumab in AQP4-IgG-positive neuromyelitis optica spectrum disorder. [PDF]
Koc ER +40 more
europepmc +1 more source

