Results 271 to 280 of about 474,325 (341)

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

Thermoresponsive BrushGel Microcarriers for Efficient Cell Expansion and Enzyme‐Reduced Harvesting

Advanced Healthcare Materials, EarlyView.
Askari et al, report on temperature‐responsive microcarriers to minimize enzyme use and cost in dynamic cultures. Abstract Scaling up cell therapy requires efficient expansion of high‐quality cells. Microcarrier(MC)‐based systems offer high surface‐to‐volume ratios and reduce culture media usage.
Esfandyar Askari, Mahdieh Shokrollahi Barough, Amir Seyfoori, Mahmood Razzaghi, Joel Alexander Ninan, Aidan B. P. Murray, Mahmoud Salkhordeh, Yuan Tan, Shirley H. J. Mei, Mohsen Akbari   +9 more
wiley   +1 more source

Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of HSK39297 in Chinese Healthy Subjects: A Phase 1 Clinical Trial. [PDF]

Clin Transl Sci
Dai Y, Wu F, Ni S, Hu X, Han Y, Jiao Y, Lu H, Liu Y, Wang L, Lin Y, Chen M, Wang C, Wu Q, Li F, Lu L.   +14 more
europepmc   +1 more source

Soft Nanocarriers as Antimicrobial Co‐Delivery Systems to Combat Resistant Infections

Advanced Healthcare Materials, EarlyView.
Soft nanocarrier‐based co‐delivery systems present a versatile and promising platform for combating antimicrobial resistance (AMR) by enabling spatiotemporally controlled, pathogen‐specific drug release. Their tunable physicochemical properties allow for the co‐encapsulation of synergistic antimicrobial agents, optimization of drug ratios, and surface ...
Anamarija Nikoletic, Evangelos Natsaridis, Timon Flathmann, Daiane P. C. Quadros, Nubia Gogniat, Oya Tagit   +5 more
wiley   +1 more source

Crovalimab: A Novel Approach in the Management of Paroxysmal Nocturnal Hemoglobinuria. [PDF]

Health Sci Rep
Jalal L, Ahmed M, Khalid A.
europepmc   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Systemic lupus erythematosus as the paradigm for understanding the complex immune relationships and therapeutic opportunities for targeting complement in autoimmune diseases. [PDF]

Immunobiology
Holers VM.
europepmc   +1 more source

Complement Factor B Deficiency Is Dispensable for Female Fertility but Affects Microbiome Diversity and Complement Activity. [PDF]

Int J Mol Sci
Sunamoto M, Morohoshi K, Sato B, Mihashi R, Inui M, Yamada M, Miyado K, Kawano N.   +7 more
europepmc   +1 more source

Is COVID-19 Coagulopathy a Thrombotic Microangiopathy? A Prospective, Observational Study. [PDF]

Int J Mol Sci
Silingardi M, Zappulo F, Dormi A, Pizzini AM, Donadei C, Cappuccilli M, Fantoni C, Zaccaroni S, Pizzuti V, Cilloni N, Tantillo S, Guidi A, Mancini R, La Manna G, Comai G.   +14 more
europepmc   +1 more source

C3 Glomerulonephritis Associated With Unusual IgG4 Antifactor H in IgG4-related Disease. [PDF]

Kidney Med
Dalmas P, Bobot M, Jourde-Chiche N, Bruno J, Burtey S, Daniel L, El-Sissy C, Fremeaux-Bacchi V, Jorquera A, Javaugue V, Schleinitz N, Ebbo M.   +11 more
europepmc   +1 more source