Results 281 to 290 of about 474,325 (341)

Immunological dysfunction of children with severe parapneumonic effusion. [PDF]

Front Pediatr
Rózsai B, Simon D, Berki T, Kiss G, Mosdósi B.   +4 more
europepmc   +1 more source

CTx001 for geographic atrophy: a gene therapy expressing soluble, truncated complement receptor 1 (mini-CR1)

Rathi S, Didangelos A, Pisarenka S, Green R, Emery-Billcliff P, Patel N, Whalley P, Zamira P, Tilakaratna V, Szula E, Hasan R, Munye M, Unwin RD, Bishop PN, Keefe D, Clark SJ.   +15 more
europepmc   +1 more source

Collectin-11 regulates osteoclastogenesis and bone maintenance via a complement-dependent mechanism

Howard MC, Farrar CA, Nauser CL, Jeon Y, Polycarpou A, Smolarek D, Greenlaw R, Garred P, Vizitiu DA, Mukhopadhyay S, Sacks SH.   +10 more
europepmc   +1 more source

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The complement alternative pathway and hemostasis

Immunological Reviews, 2022
The complement and hemostatic systems are complex systems, and both involve enzymatic cascades, regulators, and cell components—platelets, endothelial cells, and immune cells.
M. Noris, M. Galbusera
semanticscholar   +3 more sources

The Complement Alternative Pathway and Preeclampsia

Current Hypertension Reports, 2018
Significant and intricate immune adaptations are essential for the establishment and maintenance of normal pregnancy. Preeclampsia is a morbid, potentially life-threatening disease for both mother and neonate that occurs uniquely in pregnancy, at least in part, due to maternal immune maladaptation.
Layan Alrahmani, M. Willrich
semanticscholar   +4 more sources

Initiation of the alternative pathway of complement and the history of “tickover”

Immunological Reviews, 2022
The evolutionary history of complement suggests that the alternative pathway arose prior to the arrival of the classical and lectin pathways. In these pathways, target specificity is provided by antibodies and sugar specific lectins.
M. K. Pangburn
semanticscholar   +1 more source

Alternative Complement Pathway in Schizophrenia [PDF]

Neurochemical Research, 2010
In the present study, we evaluated functional activity of the alternative pathway of complement in schizophrenia by measuring the alternative pathway hemolytic activity (AH50) of complement as well as hemolytic activity of the complement C3 component (C3H50) in the blood of patients with schizophrenia and healthy subjects.
Andranik Chavushyan, Anna Boyajyan, Aren Khoyetsyan   +2 more
openaire   +2 more sources

The alternative pathway of complement

Springer Seminars in Immunopathology, 1984
The alternative pathway of complement activation provides the host with a humoral component of the natural defense mechanisms against infectious agents. The six plasma proteins involved in recognition and activation perform a continuous surveillance function that does not require specific antibody to recognize potential pathogens.
Michael K. Pangburn, Hans J. Müller-Eberhard   +1 more
openaire   +3 more sources

Abnormalities in the alternative pathway of complement in psoriasis

Clinical and Experimental Dermatology, 1982
Summary Some of the immunologic aspects of psoriasis suggest that complement may be involved in the pathophysiology of that disease. The purpose of this work was to examine the complement system in more detail in 20 patients with psoriasis. Classical pathway determinations, RCH50 and factor B levels were normal or elevated.
Joan R.Urmson, Wayne M.Marley, Wayne M.Marley, Patricia W. Belew, Roger E Spitzer, E.William Rosen-Berg, E.William Rosen-Berg, Ann E Stitzel   +7 more
openaire   +3 more sources