Results 141 to 150 of about 3,236,190 (349)

Complement Receptor C5aR1 Plays an Evolutionarily Conserved Role in Successful Cardiac Regeneration

Circulation, 2018
N. Natarajan, Yamen Abbas, D. M. Bryant, D. M. Bryant, D. M. Bryant, J. González-Rosa, Michka Sharpe, Aysu Uygur, Lucas H. Cocco-Delgado, N. Ho, Norma P. Gerard, Norma P. Gerard, Norma P. Gerard, Craig Gerard, Craig Gerard, Craig Gerard, C. Macrae, Caroline E. Burns, C. Burns, Jessica L. Whited, Jessica L. Whited, Jessica L. Whited, Richard T. Lee, Richard T. Lee   +23 more
semanticscholar   +1 more source

Storage of Transfusion Platelet Concentrates Is Associated with Complement Activation and Reduced Ability of Platelets to Respond to Protease-Activated Receptor-1 and Thromboxane A2 Receptor [PDF]

Linnéa Andersson, Dick J. Sjöström, Huy Quang Quach, Kim Hägerström, Lisa Hurler, Erika Kajdácsi, László Cervenak, Zoltán Prohászka, Erik J. M. Toonen, Camilla Mohlin, Tom Eirik Mollnes, Per Sandgren, Ivar Tjernberg, Per H. Nilsson   +13 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Critical role for complement receptor C5aR2 in the pathogenesis of renal ischemia‐reperfusion injury

The FASEB Journal, 2017
Felix Poppelaars, M. B. Werkhoven, J. Kotimaa, Zwanida J. Veldhuis, Albertina Ausema, Stefan G. M. Broeren, J. Damman, J. C. Hempel, H. Leuvenink, M. Daha, W. Son, C. Kooten, Ronald P. Os, J. Hillebrands, M. Seelen   +14 more
semanticscholar   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

New Insights into the Complement Receptor of the Ig Superfamily Obtained from Structural and Functional Studies on Two Mutants. [PDF]

Immunohorizons, 2023
Duan H, Abram TG, Cruz AR, Rooijakkers SHM, Geisbrecht BV.   +4 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Complement receptor 1 is expressed on brain cells and in the human brain. [PDF]

Glia, 2023
Daskoulidou N, Shaw B, Torvell M, Watkins L, Cope EL, Carpanini SM, Allen ND, Morgan BP.   +7 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Protocol for cell-based screening assay to measure ERK1/2 phosphorylation as a readout for complement receptor activation. [PDF]

STAR Protoc, 2023
Li XX, Woodruff TM.
europepmc   +1 more source