Results 181 to 190 of about 3,236,190 (349)

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

Complement receptor <i>C3ar1</i> deficiency does not alter brain structure or functional connectivity across early life development. [PDF]

Brain Commun
Lemmik H, Kim E, MacNicol E, Maselli D, Bernanos M, Li Z, Abdullahi D, Walters E, Serrano Navacerrada ME, Zhou W, Ivetic A, Cash D, Westacott L.   +12 more
europepmc   +1 more source

Identification of a novel mutation in complement receptor 2 in Chinese familial systemic lupus erythematosus. [PDF]

Arch Rheumatol, 2022
Tang Y, Luo Y.
europepmc   +1 more source

Aggregation of complement receptors on human neutrophils in the absence of ligand. [PDF]

, 1987
P A Detmers, Samuel D. Wright, Eva M. Olsen, Beth Kimball, Zanvil A. Cohn   +4 more
openalex   +1 more source

Streptococcus pneumoniae Endopeptidase O Promotes the Clearance of Staphylococcus aureus and Streptococcus pneumoniae via SH2 Domain-Containing Inositol Phosphatase 1-Mediated Complement Receptor 3 Upregulation [PDF]

, 2020
Sijie Li, Hong Zhang, Jiangming Xiao, Taixian Yuan, Zhaoche Shu, Yajun Min, Wenchun Xu, Yibing Yin, Xuemei Zhang   +8 more
openalex   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Neutrophils Require Activation to Express Functional Cell-Surface Complement Receptor Immunoglobulin. [PDF]

Front Immunol, 2022
Small AG, Perveen K, Putty T, Patel N, Quinn P, Wechalekar MD, Hii CS, Quach A, Ferrante A.   +8 more
europepmc   +1 more source

Structural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3

Proceedings of the National Academy of Sciences of the United States of America, 2013
G. Bajic, L. Yatime, Robert B Sim, T. Vorup-Jensen, G. Andersen   +4 more
semanticscholar   +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Structural insights into small-molecule agonist recognition and activation of complement receptor C3aR. [PDF]

EMBO J
Kim J, Ko S, Choi C, Bae J, Byeon H, Seok C, Choi HJ.   +6 more
europepmc   +1 more source