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Serpins and the Complement System
2011C1-inhibitor (serpin G1) is a 105 kDa inhibitor which functions as a major antiinflammatory protein in the body. It has its effects via inhibition of the proteases of the complement system and contact system of coagulation, as well as several direct effects mediated by its unique highly glycosylated N-terminal domain.
Péter Závodszky +6 more
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Evolution of the complement system
Immunology Today, 1991The ancestral form of the alternative pathway of complement activation probably originated as a primitive independent immune system. Subsequent evolution of an adaptive immune response drove the specialization of the classical pathway to connect antibody-mediated nonself recognition to the complement-dependent effector mechanisms.
John P. Atkinson, Timothy C. Farries
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2002
The complement system is a vital part of the immune system in humans. It is composed of a group of highly coupled proteins that interact with one another to effect inflammation and the humoral immunity fly. Important aspects of the function of the complement system in triggering action in humans include the following [2]: 1.
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The complement system is a vital part of the immune system in humans. It is composed of a group of highly coupled proteins that interact with one another to effect inflammation and the humoral immunity fly. Important aspects of the function of the complement system in triggering action in humans include the following [2]: 1.
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1979
The focus of discussion in this chapter will be the distribution of those items that we have analyzed as being complementizers. It will be particularly concerned with the phenomenon known traditionally as the ‘Double Relative’ construction (see the references in note 8 of Chapter 2).
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The focus of discussion in this chapter will be the distribution of those items that we have analyzed as being complementizers. It will be particularly concerned with the phenomenon known traditionally as the ‘Double Relative’ construction (see the references in note 8 of Chapter 2).
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1975
1 Components and Reactivity.- 1.1 Components.- 1.1.1 Factors of the Classical Pathway.- 1.1.2 Components of the Alternative Pathway.- 1.1.3 Late Components.- 1.2 Reactivity.- 1.2.1 Classical Pathway of Activation.- 1.2.2 Lectin Pathway of Non-self Recognition.- 1.2.3 Alternative Pathway: Activation and Regulation.- 1.2.4 Complement Attack Phase.- 1.2.5
Klaus Rother, Gerd O. Till
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1 Components and Reactivity.- 1.1 Components.- 1.1.1 Factors of the Classical Pathway.- 1.1.2 Components of the Alternative Pathway.- 1.1.3 Late Components.- 1.2 Reactivity.- 1.2.1 Classical Pathway of Activation.- 1.2.2 Lectin Pathway of Non-self Recognition.- 1.2.3 Alternative Pathway: Activation and Regulation.- 1.2.4 Complement Attack Phase.- 1.2.5
Klaus Rother, Gerd O. Till
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Introduction to the complement system
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1984Complement is the essential effector mechanism in humoral immunity to infection. Combination of antibody with antigen causes cross-linking, leading to precipitation of soluble antigens and agglutination of particular antigens, but no more.
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Genetics of the Complement System
1976After a brief history of complement genetics, general considerations and applications to our understanding of immune function, evolution, population structure and migration and forensic medicine, selected topics in complement genetics are presented. For individual complement proteins, genetic polymorphisms and deficiency states are described, as are ...
Chester A. Alper +3 more
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Activation of the Complement System
1973The complement system is a mediator of a number of biologically important reactions which range from cytotoxicity of antibody-sensitized cells, bacteria, and viruses to mediation of inflammatory processes. The components of the system are a number of normal serum proteins which are present in the circulation as functionally inactive precursor molecules.
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Brain and other central nervous system tumor statistics, 2021
Ca-A Cancer Journal for Clinicians, 2021Carol Kruchko +2 more
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