Results 161 to 170 of about 146,013 (310)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Dual-channel graph learning reveals similarity and complementarity in protein-protein interaction networks. [PDF]

PLoS Comput Biol
Tang T, Shen T, Li W, Chen Y, Yuan S, Liu Y, Yang X, Luo X.   +7 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Technological impact, generality, and complementarity of artificial intelligence patents: Evidence from Samsung Electronics. [PDF]

PLoS One
Lee S, Jung T.
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

The competing-complementarity of social media

, 2013
This study presents the unique benevolent and malevolent nature of social media, intertwined to its capabilities, which influences its role as a benefactor and a competitor.
Sedera, Darshana, Sedera, Darshana D, Palekar, Shailesh   +2 more
core  

An optimization method for flexible interconnection planning based on improved CNN-LSTM prediction and tunable relative entropy-driven chaotic evolution. [PDF]

PLoS One
Zhao X, Xing X, Guo X, Chao J, Hu D, Zhuan X.   +5 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Stability analysis of two stage stochastic mathematical programs with complementarity constraints via NLP-regularization

This paper presents numerical approximation schemes for a two stage stochastic programming problem where the second stage problem has a general nonlinear complementarity constraint: first, the complementarity constraint is approximated by a parameterized
Xu, Huifu, Lin, Gui-Hua, Liu, Yongchao
core  

The mediating role of life skills in the association of the coach-athlete relationship with youth athletes' well-being. [PDF]

Discov Ment Health
Tozetto WR, Lima COV, de Sousa Ferreira Dos Santos F, Durand-Bush N, Milistetd M.   +4 more
europepmc   +1 more source