Results 101 to 110 of about 2,466,021 (331)
PRISM: Patient Response Identifiers for Stratified Medicine [PDF]
Pharmaceutical companies continue to seek innovative ways to explore whether a drug under development is likely to be suitable for all or only an identifiable stratum of patients in the target population. The sooner this can be done during the clinical development process, the better it is for the company, and downstream for prescribers, payers, and ...
arxiv
Three-dimensional Optical Coherence Tomography Image Denoising through Multi-input Fully-Convolutional Networks [PDF]
In recent years, there has been a growing interest in applying convolutional neural networks (CNNs) to low-level vision tasks such as denoising and super-resolution. Due to the coherent nature of the image formation process, optical coherence tomography (OCT) images are inevitably affected by noise.
arxiv +1 more source
Traditional, complementary and alternative medicine use in Sub-Saharan Africa: a systematic review
Background The WHO estimates that a considerable number of people in Sub-Saharan Africa (SSA) rely on traditional, complementary and alternative medicine (TCAM) to meet their primary healthcare needs, yet there remains a dearth of research evidence on ...
Peter Bai James+3 more
semanticscholar +1 more source
Immunoregulatory mechanisms of the arachidonic acid pathway in cancer
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine+3 more
wiley +1 more source
Metasurface-Enabled On-Chip Multiplexed Diffractive Neural Networks in the Visible [PDF]
Replacing electrons with photons is a compelling route towards light-speed, highly parallel, and low-power artificial intelligence computing. Recently, all-optical diffractive neural deep neural networks have been demonstrated. However, the existing architectures often comprise bulky components and, most critically, they cannot mimic the human brain ...
arxiv
The entire mankind across the globe is suffering with COVID-19 outbreak and searching for definite vaccine or treatment for it. Every country is trying hard to get a breakthrough for defi nitive therapy in the form of antiviral therapy, plasma therapy ...
A. Shankar+3 more
semanticscholar +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
NMR based Pharmaco-metabolomics: An efficient and agile tool for therapeutic evaluation of Traditional Herbal Medicines [PDF]
Traditional Indian (Ayurvedic) and Chinese herbal medicines have been used in the treatment of a variety of diseases for thousands of years because of their natural origin and lesser side effects. However, the safety and efficacy data (including dose and quality parameters) on most of these traditional medicines are far from sufficient to meet the ...
arxiv
Background: Rosa canina L. (rose hip) has been traditionally used to treat diabetes mellitus in Iran. However, no scientific human study has determined its efficacy in diabetic patients.
Fataneh Hashem Dabaghian+6 more
doaj
IntroductionCancer is a debilitating disease with an often chronic course. One of the most taxing and prevalent sequelae in this context is cancer-related fatigue (CRF) resulting from the disease and/or associated treatments.
Eliane Timm+4 more
doaj +1 more source