Results 131 to 140 of about 5,410,212 (366)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The Alternative Appeal [PDF]

open access: yes, 2011
For decades, Americans expressed dissatisfaction with conventional cancer treatments. I examine the appeal of biological alternatives to surgery, chemotherapy, and radiation therapy for patients with cancer.
DeRoo, Courtney
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

The benefits of hypnosis as an adjunct treatment for bronchial asthma–a clinical trial

open access: yesMedisan
Introduction: Bronchial asthma is a prevalent chronic respiratory disease associated with significant morbidity and healthcare costs. Complementary and alternative therapies, including hypnosis, have gained interest as potential adjunct treatments for ...
Yaimarelis Picó Carela   +4 more
doaj  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

“Complement-ary” Therapies for Age-Related Macular Degeneration

open access: yesOphthalmology Science, 2022
Jonathan B. Lin, MD, PhD   +1 more
doaj   +1 more source

Traditional and Complementary Medicine According to Physicians in A Tertiary Hospital in Turkey: A Cross-Sectional Study

open access: yesInternational Journal of Traditional and Complementary Medicine Research
Objective: This study aims to assess the use of Traditional and Complementary Medicine (CAM) practices and the attitudes and behaviors of physicians working in the health sector about CAM.Method: Our study was planned as a cross-sectional observational ...
Seçil Gunher Arıca   +3 more
doaj   +1 more source

Complementary and conventional providers in cancer care: experience of communication with patients and steps to improve communication with other providers

open access: yesBMC Complementary and Alternative Medicine, 2017
Background Effective interdisciplinary communication is important to achieve better quality in health care. The aims of this study were to compare conventional and complementary providers’ experience of communication about complementary therapies and ...
Trine Stub   +4 more
doaj   +1 more source

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