Results 291 to 300 of about 5,214,305 (354)
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
FEBS Open Bio, EarlyView.Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source
Multi‐institutional study on image quality for a novel CBCT solution on O‐ring linac
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Introduction This work presents a multi‐institutional study on image quality provided by a novel cone beam computed tomography (CBCT). The main goal is to investigate the consistency of imaging performance across multiple institutions.
Luis Agulles‐Pedrós +11 more
wiley +1 more source
A review of artificial intelligence in brachytherapy
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen +4 more
wiley +1 more source
Complementary and Alternative Medicine (CAM) Therapies in the Treatment of Meniere's Syndrome: Reviewing the Evidence for Acupuncture [PDF]
, 2008 Bennett, T +4 more
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Monte Carlo modeling of radiation dose from radiation therapy with superficial x‐rays
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Introduction Superficial x‐rays (50–100 kVp) are used for treating non‐melanoma skin cancer and intraoperative radiation therapy (IORT). At these energies, the photoelectric effect significantly increases absorbed dose to bone compared to soft tissue.
Reham Barghash +3 more
wiley +1 more source
Complementary therapies for patients with systemic sclerosis. [PDF]
J Scleroderma Relat Disord, 2019 Showalter K +6 more
europepmc +1 more source
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Current radiotherapy practices rely on manual contouring of CT scans, which is time‐consuming, prone to variability, and requires highly trained experts. There is a need for more efficient and consistent contouring methods. This study evaluated the performance of the Varian Ethos AI auto‐contouring tool to assess its potential integration into
Robert N. Finnegan +6 more
wiley +1 more source