Results 141 to 150 of about 304,923 (295)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Exploring the potential of acupuncture as a complementary therapy for post-COVID skin hyperpigmentation: a case report. [PDF]

Front Med (Lausanne)
Xue Y, Li X, Duan Y, Gao Q, Zhao Y, Wu X, Wu Z.   +6 more
europepmc   +1 more source

Electroacupuncture as a rapid-onset and safer complementary therapy for depression: A systematic review and meta-analysis. [PDF]

Front Psychiatry, 2022
Zhang Z, Cai X, Liang Y, Zhang R, Liu X, Lu L, Huang Y.   +6 more
europepmc   +1 more source

Data for: "Enrichment Sessions as a Complementary Therapy for Hospitalized Cats: Implications for Stress Reduction and Sporotrichosis’ Lesion Recovery"

, 2023
Sabrina Tiemi Morais Sato, Ruan R. Daros
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Inhaling Peppermint Essential Oil as a Promising Complementary Therapy in the Treatment of Nausea and Vomiting. [PDF]

J Clin Med
Gergő D, Garmaa G, Tóth-Mészáros A, To UND, Fehérvári P, Harnos A, Hegyi P, Nagy R, Bánvölgyi A, Ványolós A, Csupor D.   +10 more
europepmc   +1 more source

Alternative, Integrative, and Complementary Therapy [PDF]

openalex   +1 more source

Complementary therapies for acne vulgaris [PDF]

, 2015
Huijuan Cao, Guoyan Yang, Yuyi Wang, Jianping Liu, Caroline Smith, Hui Luo, Yueming Liu   +6 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

EEG patterns in critically ill comatose patients receiving complementary therapy with aromatic orifice-opening herbs: A preliminary retrospective observational study. [PDF]

Medicine (Baltimore)
Shang WJ, Chen SJ, Qiu CL, Qiu H, Zhang LP, Jiang Y.   +5 more
europepmc   +1 more source