Results 1 to 10 of about 120,809 (198)
Complement in trauma—Traumatised complement? [PDF]
British Journal of Pharmacology, 2020 Physical trauma represents a major global burden. The trauma‐induced response, including activation of the innate immune system, strives for regeneration but can also lead to post‐traumatic complications. The complement cascade is rapidly activated by damaged tissue, hypoxia, exogenous proteases and others.
Markus S. Huber‐Lang +4 more
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Subgraph Complementation [PDF]
Algorithmica, 2020 AbstractA subgraph complement of the graph G is a graph obtained from G by complementing all the edges in one of its induced subgraphs. We study the following algorithmic question: for a given graph G and graph class $${\mathscr {G}}$$G, is there a subgraph complement of G which is in $${\mathscr {G}}$$G?
Fomin, Fedor V. +3 more
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SUBSTITUTING COMPLEMENTS [PDF]
Journal of Competition Law & Economics, 2006 The presence of multiple sellers in the provision of (nonsubstitutable) complementary goods leads to outcomes that are worse than those generated by a monopoly (with a vertically integrated production of complements), a problem known in the economic literature as complementary oligopoly and recently popularized in the legal literature as the tragedy of
PARISI, FRANCESCO, G. Dari Mattiacci
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WormBook, 2005 Mutations in many genes can result in a similar phenotype. Finding a number of mutants with the same phenotype tells you little about how many genes you are dealing with, and how mutable those genes are until you can assign those mutations to genetic loci. The genetic assay for gene assignment is called the complementation test.
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Journal of Graph Theory, 1985 AbstractWe prove that, with very few exceptions, every graph of order n, n − 0, 1(mod 4) and size at most n − 1, is contained in a self‐complementary graph of order n. We study a similar problem for digraphs.
Benhocine, A., Wojda, A.P.
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source
Complementing the inflammasome [PDF]
Immunology, 2016 SummaryThe innate immune system is an ancient surveillance system able to sense microbial invaders as well as aberrations in normal cell function. No longer viewed as a static and non‐specific part of immunity, the innate immune system employs a plethora of specialized pattern recognition sensors to monitor and achieve homeostasis; these include the ...
Martha, Triantafilou +3 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási +14 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta +6 more
wiley +1 more source