Results 71 to 80 of about 294,344 (225)

Experiment on complementizer-less subject relatives in English

, 2021
This is an acceptability rating experiment assessing the acceptability of complementizer-less subject relatives in English. 
Foppolo, Francesca, Cecchetto, Carlo, Konrad, Ingrid, Donati, Caterina   +3 more
core  

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Molecular Diagnosis in Children With Febrile Seizures: Beyond the Conventional Clinical Classification

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Febrile seizures (FS) are currently classified as simple or complex primarily to describe seizure characteristics, with limited ability to identify the underlying etiology. We evaluated whether molecular diagnosis could complement conventional classification and improve the diagnosis and management of FS.
Jia Wang, Mengna Zhang, Yangyang Wang, Xiuyu Shi, Baoguang Li, Xiuxia Wang, Dan Sun, Sanqing Xu, Jianbo Zhao, Lijun Du, Qiming Pang, Xiaoming Liu, Chunhui Tang, Xiaohua Li, Jiuwei Li, Yanli Ma, Jianxiang Liao, Gulixian Abudureyimu, Jianmin Liang, Yuan Wang, De Wu, Jian Wu, Liping Zou   +22 more
wiley   +1 more source

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source

The deletion restriction method for plane curve germ complement

, 2020
We study the cohomology jump loci of rank one local systems for the plane curve germ complement by the deletion restriction method. In particular, the deletion restriction type results in this case only depend on the linking numbers between the irreducible components of the plane curve germ.
openaire   +2 more sources

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

The evolution of a coordinator from a vocative source: the case of the disjunctive ja: in Jordanian Arabic. [PDF]

Heliyon, 2021
Jaradat AA, Jaradat AA, Al-Taher MA.
europepmc   +1 more source

Construction and Complementation of In-Frame Deletions of the Essential Escherichia coli Thymidylate Kinase Gene [PDF]

Applied and Environmental Microbiology, 2006
ABSTRACT This work reports the construction of Escherichia coli in-frame deletion strains of tmk , which encodes thymidylate kinase, Tmk. The tmk gene is located at the third position of a putative five-gene operon at 24.9 min on the E. coli
openaire   +5 more sources

Neuromorphic Training of VO2 Device at Behavioral Timescale Inspired by the Plasticity of CA1 Neurons of Live Mouse Brain

Advanced Materials Interfaces, EarlyView.
A VO2 device can act as a functional analog for behavioral timescale synaptic plasticity noted in the mouse brain by current pulsing. ABSTRACT Realizing biologically relevant plasticity rules in hardware is a central goal in neuromorphic computing.
Siddharth Kumar, Mohamed Adel, Christine Grienberger, Shriram Ramanathan   +3 more
wiley   +1 more source

Identifying Physical Interactions in Contact‐Based Robot Manipulation for Learning from Demonstration

Advanced Robotics Research, EarlyView.
Robots can learn manipulation tasks from human demonstrations. This work proposes a versatile method to identify the physical interactions that occur in a demonstration, such as sequences of different contacts and interactions with mechanical constraints.
Alex Harm Gert‐Jan Overbeek, Herman van der Kooij, Douwe Dresscher, Mark Vlutters   +3 more
wiley   +1 more source