FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
How complementor partners add value to e-tailers? [PDF]
, 2014 The emerging technology and concept of web 2.0 impact the value creation model of E-tailers nowadays. The past decade has seen the rapid development of complementors in the e-tailing market.
Zhang, Yingrui
core
Charting new courses to enter foreign markets: Conceptualization, theoretical framework, and research directions on non-traditional entry modes. [PDF]
J Int Bus Stud, 2022 Brouthers KD, Chen L, Li S, Shaheer N.
europepmc +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Scaling digital solutions for wicked problems: Ecosystem versatility. [PDF]
J Int Bus Stud, 2023 Tatarinov K, Ambos TC, Tschang FT.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Digital Sourcing Within Digital Platform Ecosystems: A Complementor Perspective
This multi-case study explores the digital sourcing practices of two complementor firms within two digital platform ecosystems (DPE) owned by Microsoft and SAP, respectively.
Bourdeau, Simon +3 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Digital Platform Governance for Complementor Engagement [PDF]
Over the last two decades, digital platforms (DPs) such as Amazon, Airbnb, and Uber have transformed various industries by enabling interactions and resource exchanges among diverse economic entities. Unlike traditional businesses that control the linear
Zhou, Vivian
core +1 more source