Psychological safety as a key moderator: exploring digital leadership, flow and improvisational ability through a dual PLS-SEM and fsQCA approach. [PDF]
Zhang J, Khan AY, Akhtar M, Khan AY.
europepmc +1 more source
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Clinical controls and model calibration as keys to complete blood count-based studies of pediatric fistula-in-ano. [PDF]
Zhang SY, Shi JB.
europepmc +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Using AI Algorithms and Machine Learning in the Analysis of a Bio-Purification Method (Therapeutic Emesis, Known as "Vamana Karma"): Protocol for a Mixed Methods Study. [PDF]
Rani P +5 more
europepmc +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Alignment of Large Language Model Responses With Human Therapists in Motivational Interviewing.
Teferra BG +11 more
europepmc +1 more source
How do patients with primary hypertension assess different endpoints of their treatment? a survey using analytic hierarchy process. [PDF]
Dintsios CM, Chernyak N.
europepmc +1 more source
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source

