Results 81 to 90 of about 3,414,694 (256)

Safety and Consistency Verification for a High-level Permission Assignment Constraint [PDF]

open access: yesJisuanji gongcheng, 2018
Existing permission assignment constraints pay more attention to ensure the safety,however the availability for the system is ignored.Aiming at this problem,this paper proposes a High-level Permission Assignment (HPA)constraint to satisfy the safety and ...
WANG Zheng,XU Dewu,HAN Jianmin,LU Jianfeng
doaj  

Managing the consistency of distributed documents [PDF]

open access: yes, 2005
Many businesses produce documents as part of their daily activities: software engineers produce requirements specifications, design models, source code, build scripts and more; business analysts produce glossaries, use cases, organisation charts, and ...
Nentwich, C., Nentwich, Christian
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

A Natural-Rule-Based-Connection (NRBC) Method for River Network Extraction from High-Resolution Imagery

open access: yesRemote Sensing, 2015
This study proposed a natural-rule-based-connection (NRBC) method to connect river segments after water body detection from remotely sensed imagery. A complete river network is important for many hydrological applications.
Chuiqing Zeng   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Time Consistency of Fiscal and Monetary Policy: A Solution [PDF]

open access: yes
This paper demonstrates how time consistency of the Ramsey policy–the optimal fiscal and monetary policy under commitment–can be achieved. Each government should leave its successor with a unique maturity structure for the nominal and indexed debt, such ...
Persson , Torsten   +2 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Pointwise universal consistency of nonparametric density estimators. [PDF]

open access: yes
This paper presents sufficient conditions for pointwise universal consistency of nonparametric delta estimators and shows the application of these conditions for some classes of nonparametric estimators.Delta estimators; Pointwise approximation ...
Vidal-Sanz, Jose M.
core  

Home - About - Disclaimer - Privacy