Results 101 to 110 of about 292,611 (264)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
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FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
, 2011 In this paper, we provide three new operations on fuzzy graphs; namely direct product, semi-strong product and strong product.We give sufficient conditions for each one of them to be complete and we show that if any of these products is complete, then at least one factor is a complete fuzzy graph. Moreover, we introduce and study the notion of balanced
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FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
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Discrete Mathematics, 2006 Let \(S= (S_1,\dots, S_n)\) be an out-degree vector of an orientation of a graph \(G\) with vertices \(1,\dots, n\). According to the partial order \(\succeq\) on the nonnegative integral vectors [see \textit{H. J. Ryser}, J. Algebra 10, 246--261 (1968; Zbl 0167.28001)] \(S^r_G\succeq S\succeq S^l_G\), \(\sum^n_{i=1} s_i= |E(G)|\) and \(0\leq s_i\leq ...
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FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
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Balanced rank distribution labeling of ladder graphs, complete graphs and complete bipartite graphs
, 2021 A balanced rank distribution labeling of a graph G of order n is a new kind of vertex labeling from {1, 2, 3, ..., k}(n = 6, complete graphs K-n for n >= 3 and complete bipartite graphs K-n/2,K-n/2 for even n >= 4 have been investigated and obtained the results on balanced rank distribution number (brd(G)) for the given graphs as follows: (i) brd(L-n/2)
Hemalatha, Palanisamy, Gokilamani, S.
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