Molecular genotyping of placental site and epithelioid trophoblastic tumours; female predominance [PDF]
, 2016 OBJECTIVE: To investigate a large series of placental site trophoblastic tumours (PSTT) and epithelioid trophoblastic tumours (ETT) and determine the relationship between their development and the type and sex of both the immediately antecedent and ...
Fisher, RA +4 more
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Assessment of cell proliferation in hydatidiform mole using monoclonal antibody MIB1 to Ki-67 antigen [PDF]
, 1994 Aims - To assess the role of Ki67 immunoreactivity in predicting the clinical progress of hydatidiform mole. Methods - Tissue from 87 hydatidiform moles, 11 normal first trimester placentas, 11 normal term placentas and 17 spontaneous abortions were ...
Cheung, ANY +3 more
core +2 more sources
Stem Cell Research, 2021 Recurrent hydatidiform mole (RHM) is characterized by the occurrence of at least twice hydatidiform mole. Unlike sporadic complete hydatidiform moles (CHMs), which are androgenetic with 2 paternal chromosomes, CHMs associated with familial recurrence are
Tingyu Gong +5 more
doaj +1 more source
Telomerase activity in gestational trophoblastic disease [PDF]
, 1999 Aims - To investigate the pattern of telomerase activity in hydatidiform mole as compared with normal placenta and choriocarcinoma, and to determine the prognostic significance of telomerase activity in hydatidiform mole. Methods - Telomerase activity in
Cheung, ANY +5 more
core +1 more source
Septic shock in a woman with a hydatidiform mole: A case report
Case Reports in Women's Health, 2022 Hydatidiform moles can be fatal because of the risk of massive bleeding or thyroid storm; however, they rarely occur concomitantly with sepsis. We present herein the case of a woman with a hydatidiform mole with septic shock.
Yuki Yoshimoto +5 more
doaj +1 more source
Lack of involvement of known DNA methyltransferases in familial hydatidiform mole implies the involvement of other factors in establishment of imprinting in the human female germline [PDF]
, 2003 BACKGROUND: Differential methylation of the two alleles is a hallmark of imprinted genes. Correspondingly, loss of DNA methyltransferase function results in aberrant imprinting and abnormal post-fertilization development.
Bonthron, D.T. +7 more
core +3 more sources
Early diagnosis and treatment of hydatidiform mole in adolescent pregnant woman [PDF]
, 2021 Hydatidiform mole belongs to the spectrum of gestational trophoblastic disorders in which abnormal conception leads to excess placental tissue formation in the absence of fetal development. The incidence of hydatidiform mole is quite rare so that not all
Kaspan, Kaspan +1 more
core +2 more sources
Obstetrics and Gynecology International, 2018 Objective. We sought to determine the prevalence of and factors associated with hydatidiform molar gestations amongst patients undergoing uterine evacuation at Mbarara Regional Referral Hospital (MRRH), Mbarara, Uganda. Methods.
Olivier Mulisya +11 more
doaj +1 more source
p21(WAF1/CIP1) expression in gestational trophoblastic disease: correlation with clinicopathological parameters, and Ki67 and p53 gene expression [PDF]
, 1998 Background--The p21(WAF1/CIP1) gene mediates growth arrest by inhibiting G 1 cyclin dependent kinases and has been considered as a downstream effector of the tumour suppressor gene p53.
Cheung, ANY +4 more
core +2 more sources
Hydatidiform mole and gestational trophoblastic disease [PDF]
, 2009 A mola hidatiforme é uma complicação relativamente infrequente da gravidez, mas com potencial para evolução para formas que necessitam de tratamento sistêmico e podem ser ameaçadoras da vida.
ANDRADE, Jurandyr Moreira de
core +2 more sources